Progressive Multifocal Leukoencephalopathy

Our study demonstrates that apoptosis occurs in oligodendrocytes associated with demyelinated lesions of patients with both HIV-associated and non-HIV-associated PML. There were no differences in degree, location, or type of infected or apoptotic cells between patients with HIV-associated and non-HIV-associated PML. The extent of apoptosis did not correlate with the presence or intensity of host inflammatory response. Accumulation of viral particles in nuclei of infected cells made it difficult to identify morphologic changes in the nucleus typically associated with apoptosis.

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Progressive Multifocal Leukoencephalopathy and Relapsing-Remitting Multiple Sclerosis

Boster¹,

Hreha²,

Berger³

et al. 2009

Arch Neurol

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Progressive Multifocal Leukoencephalopathy

Abstract: In order to make these reviews as Faculty comprehensive and accessible as possible, peer review takes place before publication; the referees are listed below, but their reports are not formally published.

Cited by 124 publications

References 84 publications

Progressive Multifocal Leukoencephalopathy Complicating Wiskott-Aldrich Syndrome

Progressive Multifocal Leukoencephalopathy Complicating Wiskott-Aldrich Syndrome

Progressive Multifocal Leukoencephalopathy and Apoptosis of Infected Oligodendrocytes in the Central Nervous System of Patients With and Without AIDS

Progressive Multifocal Leukoencephalopathy and Relapsing-Remitting Multiple Sclerosis

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