Progressive insights into fibrosarcoma diagnosis and treatment: leveraging fusion genes for advancements
Xiaodi Tang,
Xin Hu,
Yang Wen
et al.
Abstract:Fibrosarcoma, originating from fibroblast cells, represents a malignant neoplasm that can manifest across all genders and age groups. Fusion genes are notably prevalent within the landscape of human cancers, particularly within the subtypes of fibrosarcoma, where they exert substantial driving forces in tumorigenesis. Many fusion genes underlie the pathogenic mechanisms triggering the onset of this disease. Moreover, a close association emerges between the spectrum of fusion gene types and the phenotypic expre… Show more
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