Progressive Anemia and Left Upper Quadrant Pain in a Patient With Polycythemia Vera

Roberts, Jordan; Morales, Mariela; Rice, Lawrence

doi:10.1001/jama.2014.117

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Discussion and Review Of The Literature1

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2023

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Cited by 4 publications

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“…Hematologic malignancies, including myelofibrosis can rarely lead to a spontaneous splenic rupture [ 14 , 15 , 16 ]. Cases have even been described where the initial presentation of myelofibrosis was abdominal distention due to splenomegaly with subcapsular hematoma [ 16 ].…”

Section: Discussion and Review Of The Literaturementioning

confidence: 99%

Severe ARDS due to Ruxolitinib discontinuation syndrome: case presentation and literature review

Houthuys¹,

Wilmer²,

Peetermans³

et al. 2022

Heliyon

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Section: Discussion and Review Of The Literaturementioning

confidence: 99%

Severe ARDS due to Ruxolitinib discontinuation syndrome: case presentation and literature review

Houthuys¹,

Wilmer²,

Peetermans³

et al. 2022

Heliyon

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“…Atraumatic spontaneous splenic rupture occurs in the setting of abnormal spleen pathology. Causes include congenital hemolytic anemias, infections (mononucleosis, malaria, endocarditis); infiltrative disorders (amyloidosis, Gaucher's disease); lymphoproliferative disorders; medications (anticoagulants, granulocyte colony-stimulating factor, thrombolytics); myeloproliferative disorders; nonhematologic malignancies; pancreatitis; and portal hypertension [7]. Symptoms are left upper quadrant pain, guarding, hemodynamic instability, and left shoulder pain from diaphragmatic irritation.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous splenic rupture in polycythemia vera

Moore¹,

Fleming²,

Rogers³

2018

A Rare Benign Lesion in the Lung: Clear Cell “Sugar” Tumor (CCST)

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Atraumatic spontaneous splenic rupture is rare and occurs in the setting of spleen pathology from a myriad of causes, including myeloproliferative disorders. Only four previously reported cases of atraumatic spontaneous splenic rupture associated with polycythemia vera exist. We report the fifth case, which also is the first with severe thrombocytosis requiring multiple plateletpheresis despite medical therapy and excellent long-term control. In addition to reporting the fifth case of spontaneous splenic rupture in a polycythemia vera patient, we also review the risks associated with splenectomy in patients with polycythemia vera and therapies that can prevent spontaneous splenic rupture.

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Portal vein thrombosis as the presenting manifestation of JAK2 positive myeloproliferative neoplasm

Jeon

Mehta

Hudson

et al. 2023

The American Journal of the Medical Sciences

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Progressive Anemia and Left Upper Quadrant Pain in a Patient With Polycythemia Vera

Cited by 4 publications

References 9 publications

Severe ARDS due to Ruxolitinib discontinuation syndrome: case presentation and literature review

Severe ARDS due to Ruxolitinib discontinuation syndrome: case presentation and literature review

Spontaneous splenic rupture in polycythemia vera

Portal vein thrombosis as the presenting manifestation of JAK2 positive myeloproliferative neoplasm

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