Progression of obstructive sleep apnoea syndrome in Japanese patients

Hayashida, Kentaro; Kobayashi, Mina; Namba, Kazuyoshi; Ueki, Yoichiro; Nakayama, Hideaki; Ito, Eiki; Higami, Shigeru; Inoue, Yuichi

doi:10.1007/s11325-015-1286-8

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…These include studies by Ancoli-Israel et al ., 32 Sforza et al . 26 and Hayashida et al 25 On further analysis of the Ancoli-Israel et al ., 32 study in 1993, when controlled for BMI, there was no significant change in Respiratory Disturbance Index or sleep indices over 8.5 years of follow up. This suggested that the reported OSA regression may have been potentially caused by reduction in BMI over the study time period.…”

Section: Discussionmentioning

confidence: 98%

Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression

et al. 2022

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Objective This study was a systematic review to investigate the progression of untreated obstructive sleep apnoea in order to evaluate whether mild obstructive sleep apnoea should be treated from the standpoint of disease progression. Method The database search study outcomes that were collected included Apnea Hypopnea Index and Respiratory Disturbance Index. A meta-analysis of obstructive sleep apnoea severity over time intervals was performed. Results A total of 17 longitudinal studies and 1 randomised, controlled trial were included for review. For patients with mild obstructive sleep apnoea, mean pre-study and post-study Apnea Hypopnea Index was 5.21 and 8.03, respectively, over a median interval of 53.1 months. In patients with moderate to severe obstructive sleep apnoea, mean pre-study and post-study Apnea Hypopnea Index was 28.9 and 30.3, respectively, over a median interval of 57.8 months. Predictors for disease progression in mild obstructive sleep apnoea are patients aged less than 60 years and those with a baseline body mass index less than 25. Conclusion Mild obstructive sleep apnoea progression is observed, but it does not appear to reach any clinically significant progression to moderate or severe obstructive sleep apnoea.

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Section: Discussionmentioning

confidence: 98%

Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression

et al. 2022

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“…The effect of CPAP treatment on AHI after CPAP withdrawal is unclear, especially in OSA patients screened from the population. Many previous studies have investigated the natural evolution of OSA severity, 11 , 12 , 13 but few studies focus on the effect of CPAP treatment on that in the general population. Active OSA screening and early intervention in the general populations may be an innovative model to decrease OSA severity and improve cardiovascular outcomes.…”

Section: Introductionmentioning

confidence: 99%

The effects of long‐term continuous positive airway pressure on apnea–hypopnea index change following short‐term that withdrawal in patients with obstructive sleep apnea

Wang

Pan

2022

Clinical Respiratory J

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The effect of long‐term continuous positive airway pressure (CPAP) treatment on apnea–hypopnea index (AHI) after CPAP withdrawal remains unclear, especially in obstructive sleep apnea (OSA) patients screened from the population. To examine that, 1241 civil servants who participated in the annual physical examination were screened for OSA between September and December 2017. Screened OSA firstly underwent 1‐week CPAP adherence assessment. Then, patients with good CPAP adherence would be freely provided CPAP to continued treatment. All OSA patients were followed for 2 years. At study end, all OSA patients underwent home sleep testing (HST) again within 1 week of CPAP withdrawal. The effect of 2‐year CPAP treatment on OSA severity was investigated by using linear regression and multinominal logistic regression. In total, 103 OSA patients were screened, including 41 cases (39.8%) in CPAP treatment group and 62 cases (60.2%) in non‐CPAP treatment group. At 2‐year follow‐up, compared with baseline, in CPAP treatment group, following CPAP withdrawal, a significant decrease in AHI was observed in patients with severe OSA (P = 0.014); in non‐CPAP treatment group, a significant increase in AHI was observed in patients with moderate OSA (P = 0.028). After adjustment for confounding factors, multivariate linear regression showed that △AHI was negatively associated with CPAP treatment (β = −4.930, 95% confidence interval [CI] [−9.361, −0.500], P = 0.030). Multinominal logistic regression showed that the AHI of patients not treated with CPAP tended to be unchanged or worsened with the AHI improvement group as a reference (OR [odds ration] [95% CI], 4.555 [1.307, 15.875], P = 0.017; 6.536 [1.171, 36.478], P = 0.032). In conclusion, active OSA screening and long‐term CPAP intervention may improve the severity of severe OSA patients following short‐term CPAP withdrawal in the general population.

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Obstructive sleep apnoea is frequent in patients with type 1 diabetes

Banghoej

Nerild

Kristensen

et al. 2017

Journal of Diabetes and its Complications

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Progression of obstructive sleep apnoea syndrome in Japanese patients

Abstract: Untreated middle-aged patients may be at a high risk for worsened AHI and SpO2 even without weight gain.

Cited by 3 publications

References 33 publications

Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression

Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression

The effects of long‐term continuous positive airway pressure on apnea–hypopnea index change following short‐term that withdrawal in patients with obstructive sleep apnea

Obstructive sleep apnoea is frequent in patients with type 1 diabetes

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