Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens
Sigrid Ravn Berg,
Aida Dikic,
Animesh Sharma
et al.
Abstract:Background
Despite significant advancements in treatment strategies, multiple myeloma remains incurable. Additionally, there is a distinct lack of reliable biomarkers that can guide initial treatment decisions and help determine suitable replacement or adjuvant therapies when relapse ensues due to acquired drug resistance.
Methods
To define specific proteins and pathways involved in the progression of monoclonal gammopathy of undetermined significa… Show more
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