Progression of left ventricular diastolic function in the neonate and early childhood from transmitral color M-mode filling analysis

Erickson, Collin T; Meyers, Brett; Li, Ling; Craft, Mary; Jani, Vivek; Bliamptis, John; Moukagna, Karl Stessy Bisselou; Danford, David A.; Vlachos, Pavlos P.; Kutty, Shelby

doi:10.1038/s41390-020-1011-6

Cited by 2 publications

(1 citation statement)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…17,18 Abnormal diastolic function of left ventricle is mainly reflected in abnormal retardation of early left ventricle, impaired filling of middle and late left ventricle, and decreased myocardial compliance. 19 S/D, Ea/Aa, E/Ea, Ar, and Vp are the effective indexes for evaluating left ventricular diastolic function in clinic. 20,21 The research results of Chung et al 22 show that the left ventricular diastolic function of patients with metabolic syndrome is significantly lower than that of healthy people by echocardiography; the results of Kim et al 23 showed that echocardiography can predict the prognosis of patients with ischemic heart failure by evaluating left ventricular diastolic function.…”

Section: Discussionmentioning

confidence: 99%

Clinical application value of echocardiography in evaluating left ventricular diastolic function in patients with acute pulmonary embolism

et al. 2022

View full text Add to dashboard Cite

Objective To explore the clinical value of echocardiography in the assessment of left ventricular diastolic function in patients with acute pulmonary embolism (APE). Methods APE patients in our hospital from June 2019 to June 2021 were selected as the observation group. They were divided into low-risk group (19 cases), medium-risk group (16 cases) and high-risk group (15 cases). The non-APE people in our hospital during the same period were selected as the control group. All subjects underwent echocardiography to observe the performance of APE patients under echocardiography. The peak velocity ratio S-wave/D-wave (S/D), early diastolic annular velocity/advanced diastolic annular velocity (Ea/Aa), early filling/early diastolic annular velocity (E/Ea), and early filling/early diastolic annular velocity (E/Ea) were compared with Ar and Vp, respectively; receiver operator characteristic (ROC) curve was used to evaluate the value of echocardiography in evaluating left ventricular diastolic function in patients with APE. Results Echocardiography show different manifestations of APE patients. Compared with the control group, S/D, Ea/Aa, and Vp in the observation group were significantly decreased and E/Ea and Ar in the observation group were significantly increased ( p < 0.05). With the increase of risk stratification, S/D, Ea/Aa, and Vp gradually decreased, E/Ea and Ar gradually increased, and the difference was statistically significant ( p < 0.05). The sensitivity, specificity, accuracy, positive predictive value, negative predictive value, area under curve (AUC), and 95% CI were 89.52%, 65.57%, 72.86%, 80.82%, 75.38%, 0.730, and 0.629–0.831, respectively. Conclusion Echocardiography can effectively evaluate left ventricular diastolic function in patients with APE, and there are significant differences in left ventricular diastolic function in different risk stratification, which has important reference value for clinical diagnosis and treatment of APE.

show abstract