Progression of Keratoconus in Turkish Adult Patients

Abstract

A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To evaluate progression of keratoconus in adult patients diagnosed as keratoconus and to compare it with the disease progression in pediatric patients reported in the literature. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Five hundred and forty-seven patients diagnosed as keratoconus were reviewed retrospectively and 143 eyes of 106 adult patients were included into the study. The patients were assigned into two groups: Group I was aged 18-24 years and Group II was aged over 24 years. Data about age, best corrected visual acuity (BCVA) with glasses, spherical equivalents (SE), corneal thickness, simulated mean kerotometry (SimK) and follow-up periods were collected. The patients having progression in keratoconus were recommended a treatment with corneal collagen cross-linking. R Re es su ul lt ts s: : The mean age of the patients was 21.34±1.75 years and 30.26±5.10 years in Group I and Group II respectively. The mean follow-up period was 11.96±7.24 months in Group I and 15.44±12.6 months in Group II. The rate of the progression was 25.6% and 23.1% in Group I and Group II respectively, though there was not a significant difference (p=0.549). The rate of the progression was 24.4% in the adults recently diagnosed as keratoconus at the end of a mean follow-up period of 12.74±10.60 months. C Co on nc cl lu us si io on n: : About one fourth of the adult patients required cross-linking therapy during a one-year follow-up and 75% of the adult patients with keratoconus did not have disease progression at the end of a one-year follow-up. Before adults recently diagnosed as keratoconus are advised to have cross-linking therapy, they should be given an anti-allergic treatment and followed for the disease progression.K Ke ey y W Wo or rd ds s: : Keratoconus; corneal surgery, laser Ö ÖZ ZE ET T A Am ma aç ç: : Keratokonus tanısı konulan erişkin hastalarda keratokonus progresyonunu değerlen-dirmek ve literatürde bildirilen çocuk hastalarla karşılaştırmak. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Keratokonus tanısı alan 547 hasta retrospektif olarak incelendi, 106 hastanın 143 gözü çalışmaya dahil edildi. Çalışmada hastalar iki gruba ayrıldı. 1. grup 18-24 yaş, 2. grup 24 yaş üzeri olacak şekilde oluştu-ruldu. Hastaların dosyalarından, yaş, gözlükle en iyi görme keskinliği (EİDGK), sferik eşdeğer (SE), korneal kalınlık, ortalama simüle keratometri (SimK) ve takip süreleri not edildi. Keratokonusta progresyon görülen hastalara korneal çapraz bağlama tedavisi yapıldı. B Bu ul lg gu ul la ar r: : Hastaların ortalama yaşı, Grup 1 ve Grup 2'de sırasıyla 21,34±1,75 yıl ve 30,26±5,10 yıl idi. Grup 1'de takip süresi 11,96±7,24 ay, Grup 2'de 12,74±10,60 ay idi. Progresyon oranı, Grup 1 ve Grup 2'de sırasıyla %25,6 ve %23,1 idi (p=0,549). Erişkinlerde ortalama 12,74±10,60 ay sonunda progresyon oranı %24,4 idi. S So on nu uç ç: : Ortalama 1 yıl sonunda tüm erişkinlerin 1/4'ünde korneal çapraz-bağlama tedavisi ihtiyacı olmaktadır ve 3/4'ünde keratakonus ...