Progression of Aphasia Severity in the Chronic Stages of Stroke

Johnson, Lisa; Basilakos, Alexandra; Yourganov, Grigori; Cai, Bo; Bonilha, Leonardo; Rorden, Chris; Fridriksson, Julius

doi:10.1044/2018_ajslp--18-0123

Cited by 13 publications

(15 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although not statistically significant, the group with atypical BDNF genotype had numerically larger cortical damage and was not as far post-stroke, which are factors that may relate to long-term outcome [ 39 ]. However, those same participants also tended to be younger than those with typical BDNF genotype, which indicates a more favorable recovery from stroke and aphasia [ 40 – 42 ]. It should be noted that the baseline difference on language measures was not statistically significant once group means were adjusted for time post-stroke and lesion size, which suggests these findings may reflect other potential differences besides BDNF genotype.…”

Section: Discussionmentioning

confidence: 99%

BDNF genotype and tDCS interaction in aphasia treatment

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

BDNF genotype and tDCS interaction in aphasia treatment

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…A recent study revealed that among chronic stroke patients, improvement in language processing over several years in language processing among chronic stroke patients with aphasia is associated with more SLT sessions. 32 This study emphasized that approximately half of chronic stroke patients continue to experience recovery from aphasia even many years after stroke. The remaining half either are relatively stable or actually experience decline, an often overlooked fact that may represent an under-appreciated therapeutic target.…”

Section: Optimal Timing Of Intervention: Chronic Vs Acute Phase Of Post-strokementioning

confidence: 96%

Current Approaches to the Treatment of Post-Stroke Aphasia

Fridriksson

Hillis

2021

J Stroke

Self Cite

View full text Add to dashboard Cite

Aphasia, impairment of language after stroke or other neurological insult, is a common and often devastating condition that affects nearly every social activity and interaction. Behavioral speech and language therapy is the mainstay of treatment, although other interventions have been introduced to augment the effects of the behavioral therapy. In this narrative review, we discuss advances in aphasia therapy in the last 5 years and focus primarily on properly powered, randomized, controlled trials of both behavioral therapies and interventions to augment therapy for post-stroke aphasia. These trials include evaluation of behavioral therapies and computer-delivered language therapies. We also discuss outcome prediction trials as well as interventional trials that have employed noninvasive brain stimulation, or medications to augment language therapy. Supported by evidence from Phase III trials and large meta-analyses, it is now generally accepted that aphasia therapy can improve language processing for many patients. Not all patients respond similarly to aphasia therapy with the most severe patients being the least likely responders. Nevertheless, it is imperative that all patients, regardless of severity, receive aphasia management focused on direct therapy of language deficits, counseling, or both. Emerging evidence from Phase II trials suggests transcranial brain stimulation is a promising method to boost aphasia therapy outcomes.

show abstract

“…Types (e.g., Broca's, Wernicke's) and severities varied across studies. Most participants were at least 6 months postonset of stroke, a time period at which aphasia is considered chronic in the literature (Johnson et al, 2019). The next most common disorder population in our included studies, following aphasia, was Parkinson's disease (PD; 16%).…”

Section: Participant Characteristicsmentioning

confidence: 99%

Telepractice for Adult Speech-Language Pathology Services: A Systematic Review

2020

View full text Add to dashboard Cite

Purpose We conducted a systematic review of the literature regarding adult telepractice services (screening, assessment, and treatment) from approximately 2014 to 2019. Method Thirty-one relevant studies were identified from a literature search, assessed for quality, and reported. Results Included studies illustrated feasibility, efficacy, diagnostic accuracy, and noninferiority of various speech-language pathology services across adult populations, including chronic aphasia, Parkinson's disease, dysphagia, and primary progressive aphasia. Technical aspects of the equipment and software used to deliver services were discussed. Some general themes were noted as areas for future research. Conclusion Overall, results of the review continue to support the use of telepractice as an appropriate service delivery model in speech-language pathology for adults. Strong research designs, including experimental control, across multiple well-described settings are still needed to definitively determine effectiveness of telepractice services.

show abstract

Progression of Aphasia Severity in the Chronic Stages of Stroke

Cited by 13 publications

References 67 publications

BDNF genotype and tDCS interaction in aphasia treatment

BDNF genotype and tDCS interaction in aphasia treatment

Current Approaches to the Treatment of Post-Stroke Aphasia

Telepractice for Adult Speech-Language Pathology Services: A Systematic Review

Contact Info

Product

Resources

About