Summary. Scalar (heat or mass) transfer in the macroscale is the result of microscale diffusion and convection effects. Our fundamental hypothesis is that heat or mass transfer behavior can be synthesized from the behavior of a single, instantaneous, point source of heat or mass, and that understanding this behavior leads to an improved understanding of transport. Based on this concept, a simulation technique has been developed that involves the tracking of trajectories of heat or mass markers in a flow field, and then applying simple statistical methods to extract information about the macroscopic temperature or concentration field. The motion of these scalar markers is decomposed into a convection part, which is calculated using macroscopic flow simulations, and a diffusion part, which is simulated using a mesoscopic Monte-Carlo approach. Three different cases where this simulation methodology can been applied are presented, each one with different physics and with distinct applications. The first case is about heat transfer without convection (applied to the determination of the effective thermal conductivity of a nanocomposite material), the second case is the case of heat transfer in laminar flow (with applications in microfluidics), and the third case is the case of heat transfer with strong convective effects (applied to turbulent heat transport). The combination of a macroscopic and a mesoscopic simulation applied here allows the simulation of heat or mass transfer in cases that other conventional approaches are not feasible, and it allows the investigation of the physics of heat or mas transport in a more natural way.