Progress in the Pathologic Diagnosis of Borderline Follicular Thyroid Tumor

Abstract

With the progress of science and technology as well as the development of ultrasound technology, more and more thyroid tumors have been found. Follicular tumor is one of the most common thyroid tumors, but borderline follicular tumors are relatively rare. At present, the diagnosis of borderline follicular thyroid tumor is unclear prior to surgery, and it is difficult to identify in frozen section or even conventional section. In order to effectively improve the diagnostic sensitivity and specificity of borderline follicular thyroid tumor, this paper summarizes the new WHO (World Health Organization) classification of borderline follicular thyroid tumor along with diagnostic methods, including clinical fine needle aspiration cytology, histopathology, and molecular biology, and reviews the research progress.