Progress in Research of Nanotherapeutics for Overcoming Multidrug Resistance in Cancer
Ayitila Maimaitijiang,
Dongze He,
Dingyang Li
et al.
Abstract:Chemotherapy has been widely applied in oncotherapy. However, the development of multidrug resistance (MDR) has diminished the effectiveness of anticancer drugs against tumor cells. Such resistance often results in tumor recurrence, metastasis, and patient death. Fortunately, nanoparticle-based drug delivery systems provide a promising strategy by codelivery of multiple drugs and MDR reversal agents and the skillful, flexible, smart modification of drug targets. Such systems have demonstrated the ability to by… Show more
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