Progress in Hydroxyapatite–Starch Based Sustainable Biomaterials for Biomedical Bone Substitution Applications

Abstract

Hydroxyapatite is a calcium phosphate intensively proposed as a bone substitution material because of its resemblance to the constituents of minerals present in natural bone. Since hydroxyapatite's properties are mainly adequate for non-load bearing applications, different solutions are being tested for improving these properties and upgrading them near the target-values of natural bone. On the other hand, starch (a natural and biodegradable polymer) and its blends with other polymers have been proposed as constituents in hydroxyapatite mixtures due to the adhesive, gelling and swelling abilities of starch particles, useful in preparing well dispersed suspensions and consolidated ceramic bodies. This article presents the perspectives of

Formation and characteristics of starch‐based dual photo‐function composite hydrogel

“…Owing to possessing unique characteristics such as hydrophilicity, biodegradability, biocompatibility, and renewability, starch‐based hydrogels have been gaining growing attention . Starch‐based hydrogels have been widely applied in biomedical and food packing fields . In order to meet various requirements of practical applications, starch‐based hydrogels of different functions have been developed.…”

“…1,2 Starch-based hydrogels have been widely applied in biomedical and food packing fields. 3,4 In order to meet various requirements of practical applications, starch-based hydrogels of different functions have been developed.…”

Hydroxyapatite - Antibiotic Applications in Bone Therapy

“…Of course, the best antibacterial protection is antibiotic therapy. However, oral antibiotic therapy is sometimes ineffective, while administering an antibiotic at the location of infection is often associated with an unfavourable ratio of dosage efficiency and toxic effect [1].…”

Effect of the Chemical Composition of Simulated Body Fluids on Aerogel-Based Bioactive Composites

“…The most widely used ones are bioactive glasses [11][12][13][14][15], calcium phosphate-based cement and ceramics, biodegradable polymer-based composites, and special alloys (Ti, Zr) etc. [16][17][18][19][20][21]. All the materials have numerous advantages but none of them fulfil the requirements completely.…”