Progress in cerebrovascular disease research in the last year

Amaro, Sergio; Chamorro, Ángel

doi:10.1007/s00415-012-6408-7

Cited by 2 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cerebrovascular diseases are of a great variety with complex mechanisms, such as hereditary cerebrovascular diseases and nonhereditary cerebrovascular diseases 17–19 . There are 14 articles related to cerebrovascular disease merely published in the Journal of Neurology in 2012 20 …”

Section: Discussionmentioning

confidence: 99%

“…[17][18][19] There are 14 articles related to cerebrovascular disease merely published in the Journal of Neurology in 2012. 20 All these developments demonstrate the importance of cerebral vascular structure and cerebral blood flow at different ages for the understanding of senile encephalopathy. Because this study mainly focused on exploring whether ultrasound can be used in rat research, the brain development of SD rats of different ages was not investigated in depth.…”

Section: Quantitative Analysis Of Cerebrovascular Velocity and Heart ...mentioning

confidence: 98%

See 1 more Smart Citation

Normal cerebral blood vessels under ultrasound in SD rats of different ages

Luo

Liu

Xiong

et al. 2022

Ibrain

View full text Add to dashboard Cite

The objective of this study was to examine whether ultrasound can examine the development of cerebral vascular structure and cerebral blood flow in Sprague-Dawley (SD) rats by ultrasound in a noninvasive manner, which provides a reference for ultrasound research of SD rats. Thirty-nine SD rats (7-16 days old) were divided into seven groups according to age, and the number of SD rats in each group was, respectively, 7, 17, 1, 3, 2, 8, and 1. Ultrasound was used to detect cerebral blood vessels, cerebrovascular flow velocity, and heart rate in SD rats in the sagittal and coronal positions, and images were obtained in B-mode ultrasound. The cerebral vascular structure of 39 SD rats (7-16 days) was dynamically observed under B-ultrasound. We found that the cerebral vascular structure of the rats aged 7-10 days was clear and detectable. Rats aged 11-16 days of cerebral vascular structures became thinner and undetectable. Quantitative analysis of cerebrovascular flow rate and heart rate in rats found that there was no significant difference in cerebrovascular blood flow rate and heart rate between 7 and 8 days.Ultrasound can also be used in rat animal studies, that is, the cerebral blood flow in rats of different ages can be monitored in real-time by ultrasound in a noninvasive way.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Quantitative Analysis Of Cerebrovascular Velocity and Heart ...mentioning

confidence: 98%

Normal cerebral blood vessels under ultrasound in SD rats of different ages

Luo

Liu

Xiong

et al. 2022

Ibrain

View full text Add to dashboard Cite

show abstract

The Brain Research Hotspot Database (BRHD): A Panoramic Database of the Latest Hotspots in Brain Research

et al. 2022

View full text Add to dashboard Cite

Brain science, an emerging, dynamic, multidisciplinary basic research field, is generating numerous valuable data. However, there are still several obstacles for the utilization of these data, such as data fragmentation, heterogeneity, availability, and annotation divergence. Thus, to overcome these obstacles and construct an online community, we developed a panoramic database named Brain Research Hotspot Database (BRHD). As of 30 January 2022, the database had been integrated with standardized vocabularies from various resources, including 423,681 papers, 46,344 patents, 9585 transcriptomic datasets, 261 cell markers, as well as with information regarding brain initiatives that were officially launched and well-known scholars in brain research. Based on the keywords entered by users and the search options they set, data can be accessed and retrieved through exact and fuzzy search scenarios. In addition, for brain diseases, we developed three featured functions based on deep data mining: (1) a brain disease–genome network, which collects the associations between common brain diseases, genes, and mutations reported in the literature; (2) brain and gut microbiome associations, based on the literature related to this topic, with added annotations for reference; (3) 3D brain structure, containing a high-precision brain anatomy model with visual links to quickly connect to an organ-on-a-chip database. In short, the BRHD integrates data from a variety of brain science resources to provide a friendly user interface and freely accessible viewing and downloading environment. Furthermore, the original functions developed based on these data provide references and insights for brain research.

show abstract

Progress in cerebrovascular disease research in the last year

Abstract: Herein, we review the main papers in cerebrovascular diseases published in the Journal of Neurology over the last year.

Cited by 2 publications

References 14 publications

Normal cerebral blood vessels under ultrasound in SD rats of different ages

Normal cerebral blood vessels under ultrasound in SD rats of different ages

The Brain Research Hotspot Database (BRHD): A Panoramic Database of the Latest Hotspots in Brain Research

Contact Info

Product

Resources

About