Progress in Bioactive Polysaccharide-Derivatives: A Review

Simsek, Miray; Asiyanbi‐Hammed, Tawakalit Tope; Rasaq, Nurudeen; Hammed, Ademola Monsur

doi:10.1080/87559129.2021.1935998

Cited by 31 publications

(14 citation statements)

References 90 publications

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“…Polysaccharides with vigorous emulsifying activity and large viscosity can also be employed as potential cosmetic additives, while low-viscosity polysaccharides are advantageous in producing immediate products such as butyrate [ 60 ]. Polysaccharides with low molecular weight, excellent homogeneity, and thermal stability are useful as raw materials for polysaccharide derivatization including selenylation, esterification and sulfation [ 60 , 61 ]. Moreover, Chen et al [ 62 ] used HWE, UAE, EAE, and UEAE techniques to extract polysaccharides from Crataegus pinnatifida Bunge ; the HWE technique had the highest molecular weight compared to other methods.…”

Section: Plant Polysaccharidesmentioning

confidence: 99%

The Extraction, Functionalities and Applications of Plant Polysaccharides in Fermented Foods: A Review

Niyigaba

Liu

Habimana

2021

Foods

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Plant polysaccharides, as prebiotics, fat substitutes, stabilizers, thickeners, gelling agents, thickeners and emulsifiers, have been immensely studied for improving the texture, taste and stability of fermented foods. However, their biological activities in fermented foods are not yet properly addressed in the literature. This review summarizes the classification, chemical structure, extraction and purification methods of plant polysaccharides, investigates their functionalities in fermented foods, especially the biological activities and health benefits. This review may provide references for the development of innovative fermented foods containing plant polysaccharides that are beneficial to health.

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Section: Plant Polysaccharidesmentioning

confidence: 99%

The Extraction, Functionalities and Applications of Plant Polysaccharides in Fermented Foods: A Review

Niyigaba

Liu

Habimana

2021

Foods

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“…Furthermore, polysaccharide derivatives, such as oxidized polysaccharides, selenized polysaccharides, and sulfonated polysaccharides, have attracted extensive attention as readily available, renewable, and sustainable sources of bioactive chemical compounds. 21,22 Dialdehyde polysaccharides can be obtained by the specific ring-opening cleavage of 1,2-diols at C2 and C3 using periodate as an oxidizing agent. 23 They have received a great deal of attention as an ideal crosslinking agent of protein, especially in the field of multifunctional hydrogel preparation and tissue fixation.…”

Section: Introductionmentioning

confidence: 99%

Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification

Shi

et al. 2022

J. Mater. Chem. B

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“…Polysaccharides can directly or indirectly stimulate a variety of immune cells in mice, regulate the immune function of the body, and also exhibit hypoglycemic activity via intestinal flora in rats [ 15 , 16 , 17 ]. Increasing evidence suggests that polysaccharides may be an ideal functional food for the prevention or treatment of some diseases [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Antidiabetic Effect of Millet Bran Polysaccharides Partially Mediated via Changes in Gut Microbiome

Jin-hua

Wang

Guo

et al. 2022

Foods

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Diabetes is a type of metabolic disease associated with changes in the intestinal flora. In this study, the regulatory effect of millet bran on intestinal microbiota in a model of type 2 diabetes (T2DM) was investigated in an effort to develop new approaches to prevent and treat diabetes and its complications in patients. The effect of purified millet bran polysaccharide (MBP) with three different intragastric doses (400 mg/kg, 200 mg/kg, and 100 mg/kg) combined with a high-fat diet was determined in a streptozotocin (STZ)-induced model of T2DM. By analyzing the changes in indicators, weight, fasting blood sugar, and other bio-physiological parameters, the changes in gut microbiota were analyzed via high-throughput sequencing to establish the effect of MBP on the intestinal flora. The results showed that MBP alleviated symptoms of high-fat diet-induced T2DM. A high dosage of MBP enhanced the hypoglycemic effects compared with low and medium dosages. During gavage, the fasting blood glucose (FBG) levels of rats in the MBP group were significantly reduced (p < 0.05). The glucose tolerance of rats in the MBP group was significantly improved (p < 0.05). In diabetic mice, MBP significantly increased the activities of CAT, SOD, and GSH-Px. The inflammatory symptoms of liver cells and islet cells in the MBP group were alleviated, and the anti-inflammatory effect was partially correlated with the dose of MBP. After 4 weeks of treatment with MBP, the indices of blood lipid in the MBP group were significantly improved compared with those of the DM group (p < 0.05). Treatment with MBP (400 mg/kg) increases the levels of beneficial bacteria and decreases harmful bacteria in the intestinal tract of rats, thus altering the intestinal microbial community and antidiabetic effect on mice with T2DM by modulating gut microbiota. The findings suggest that MBP is a potential pharmaceutical supplement for preventing and treating diabetes.

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Progress in Bioactive Polysaccharide-Derivatives: A Review

Cited by 31 publications

References 90 publications

The Extraction, Functionalities and Applications of Plant Polysaccharides in Fermented Foods: A Review

The Extraction, Functionalities and Applications of Plant Polysaccharides in Fermented Foods: A Review

Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification

Antidiabetic Effect of Millet Bran Polysaccharides Partially Mediated via Changes in Gut Microbiome

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