“…During the course of treatment some patients require frequent changes of the stimulation programme to optimize the therapy, and on occasion complications associated with the treatment require surgical intervention. However, only a limited number of studies have investigated the amount of clinical input required to maintain efficacy7, 8. In addition, the incidence of suboptimal therapeutic responses and treatment‐related adverse events, and their effect on medium‐ to long‐term treatment outcome, have not been examined thoroughly.…”