Programmed cell death: a way of life for plants.

Greenberg, Jean T.

doi:10.1073/pnas.93.22.12094

Cited by 528 publications

(343 citation statements)

References 58 publications

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“…Whether HR-PCD has a role in the inhibition of pathogen growth or resistance is unclear. However, there is extensive evidence for PCD being involved in HR [35][36][37][38] (see related articles in this issue). Despite a wealth of information relating to the molecular genetics, cell biology, and biochemistry of host-pathogen interactions, relatively few studies have examined the role of the cytoskeleton in HR-PCD.…”

Section: Involvement Of the Cytoskeleton In The Hypersensitive Responmentioning

confidence: 99%

Organisation and regulation of the cytoskeleton in plant programmed cell death

2011

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Programmed cell death (PCD) involves precise integration of cellular responses to extracellular and intracellular signals during both stress and development. In recent years much progress in our understanding of the components involved in PCD in plants has been made. Signalling to PCD results in major reorganisation of cellular components. The plant cytoskeleton is known to play a major role in cellular organisation, and reorganization and alterations in its dynamics is a well known consequence of signalling. There are considerable data that the plant cytoskeleton is reorganised in response to PCD, with remodelling of both microtubules and microfilaments taking place. In the majority of cases, the microtubule network depolymerises, whereas remodelling of microfilaments can follow two scenarios, either being depolymerised and then forming stable foci, or forming distinct bundles and then depolymerising. Evidence is accumulating that demonstrate that these cytoskeletal alterations are not just a consequence of signals mediating PCD, but that they also may have an active role in the initiation and regulation of PCD. Here we review key data from higher plant model systems on the roles of the actin filaments and microtubules during PCD and discuss proteins potentially implicated in regulating these alterations.

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Section: Involvement Of the Cytoskeleton In The Hypersensitive Responmentioning

confidence: 99%

Organisation and regulation of the cytoskeleton in plant programmed cell death

2011

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“…Figure 2 illustrates the dynamics of tiller numbers for each DH line measured at 9 time points. Tiller growth is thought to be an excellent example of PCD in plants (16) because it experiences several developmental stages when rice grows. At an early stage, tiller numbers increase dramatically, corresponding to the vegetative phase in rice.…”

Section: A Worked Examplementioning

confidence: 99%

“…H 1b :u G1 u G0 and u D1 ϭ u D0 (16) or whether the detected QTL only controls the death phase with the following alternative:…”

Section: Hypothesis Testingmentioning

confidence: 99%

“…The molecular and genetic characterization of these processes has been useful to identify the specific signaling pathways that underlie a delicate balance between cell proliferation and PCD (32) and, in the ultimate, enhance our understanding of the roots of disease such as cancer (17,43). In particular, PCD has been thought to be a universal phenomenon that occurs in predictable patterns in response to environmental or developmental clues, whose study has become one of the most fascinating areas in all of biology over the last decade (16,19).…”

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Functional mapping for genetic control of programmed cell death

Cui

Zhu

2006

Physiological Genomics

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"Naturally occurring" or "programmed" cell death (PCD) in which the cell uses specialized cellular machinery to kill itself is a ubiquitous phenomenon that occurs early in organ development. Such a cell suicide mechanism that enables metazoans to control cell number and eliminate cells threatening the organism's survival has been thought to be under genetic control. In this report, we develop a novel statistical model for mapping specific genes or quantitative trait loci (QTL) that are responsible for the PCD process based on polymorphic molecular markers. This model incorporates the biological mechanisms of PCD that undergoes two different developmental stages, exponential growth and polynomial death. We derived a parametric approach to model the exponential growth and a nonparametric approach based on the Legendre function to model the polynomial death. A series of stationary and nonstationary models has been used to approximate the structure of the covariance matrix among cell numbers at a multitude of different times. The statistical behavior of our model is investigated through simulation studies and validated by a real example in rice.quantitative trait loci; semiparametric model; mean-covariance structure model; EM-Simplex algorithm; order selection

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“…Programmed cell death (PCD) or apoptosis occurs during development and in response to different environmental cues [1][2][3][4][5][6]. Apoptosis exhibits several distinct morphological features, including condensation of cytoplasm, fragmentation of nucleosomal DNA, condensation of nuclear chromatin, membrane blabbing, and appearance of apoptotic bodies [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Salinity Induced Apoptosis in Root Meristematic Cells ofRice

Yazdani¹,

Mahdieh²

2012

IJBBB

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Abstract-Salt stress is one of the most serious problems in agriculture and can induce apoptosis in plants. Cell death is induced by two modes: apoptosis and necrosis. We used a TUNEL assay and DNA gel electrophoresis on NaCl-treated cells of rice root to morphologically distinguish the mode of cell death in salt-sensitive and salt-tolerant rice cultivars. The results indicated that 500 mmol/L NaCl treatments could lead to specific features of apoptosis in root tips in both cultivars, such as DNA ladder, nuclear condense and deformation, and transferase mediated dUTP nick end labeling positive reaction, which were initiated at 4h of treatment and progressed thereafter.

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Programmed cell death: a way of life for plants.

Cited by 528 publications

References 58 publications

Organisation and regulation of the cytoskeleton in plant programmed cell death

Organisation and regulation of the cytoskeleton in plant programmed cell death

Functional mapping for genetic control of programmed cell death

Salinity Induced Apoptosis in Root Meristematic Cells ofRice

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