Programmable plasmonic phase modulation of free-space wavefronts at gigahertz rates

Smolyaninov, Alexei; Amili, Abdelkrim El; Vallini, Felipe; Pappert, S.A.; Fainman, Yeshaiahu

doi:10.1038/s41566-019-0360-3

Cited by 60 publications

(44 citation statements)

References 37 publications

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“…Therefore, it has been utilized for improving the sensitivity of plasmonic sensors. 31 In order to generate a stable and intense thermoplasmonic field, an excitation laser with 532 nm peak wavelength and 40 mW maximum optical power was applied onto the AuNI chip in the normal incident angle ( Figure 1b). In addition, optimizing the AuNI chip so that its peak absorbance wavelength was exactly at 532 nm can significantly improve the conversion efficiency of thermoplasmonic.…”

Section: Resultsmentioning

confidence: 99%

Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection

et al. 2020

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The ongoing outbreak of the novel coronavirus disease has spread globally and poses a threat to public health in more than 200 countries. Reliable laboratory diagnosis of the disease has been one of the foremost priorities for promoting public health interventions. The routinely used reverse transcription polymerase chain reaction (RT-PCR) is currently the reference method for COVID-19 diagnosis. However, it also reported a number of false-positive or -negative cases, especially in the early stages of the novel virus outbreak. In this work, a dual-functional plasmonic biosensor combining the plasmonic photothermal (PPT) effect and localized surface plasmon resonance (LSPR) sensing transduction provides an alternative and promising solution for the clinical COVID-19 diagnosis. The two-dimensional gold nanoislands (AuNIs) functionalized with complementary DNA receptors can perform a sensitive detection of the selected sequences from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through nucleic acid hybridization. For better sensing performance, the thermoplasmonic heat is generated on the same AuNIs chip when illuminated at their plasmonic resonance frequency. The localized PPT heat is capable to elevate the in situ hybridization temperature and facilitate the accurate discrimination of two similar gene sequences. Our dual-functional LSPR biosensor exhibits a high sensitivity toward the selected SARS-CoV-2 sequences with a lower detection limit down to the concentration of 0.22 pM and allows precise detection of the specific target in a multigene mixture. This study gains insight into the thermoplasmonic enhancement and its applicability in the nucleic acid tests and viral disease diagnosis.

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Section: Resultsmentioning

confidence: 99%

Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection

et al. 2020

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“…Their ground-state solutions can be effectively and reliably approximated by adaptive feedback control, whose speed is currently limited by the processing time of the SLM. A COMMUNICATIONS PHYSICS | https://doi.org/10.1038/s42005-020-0376-5 ARTICLE COMMUNICATIONS PHYSICS | (2020) 3:108 | https://doi.org/10.1038/s42005-020-0376-5 | www.nature.com/commsphys significant speedup is achievable by using ferroelectric liquidcrystal based SLMs or programmable plasmonic phase modulators 68,69 . At the present, the maximum number of accessible pixels is about 1 million and can be further increased by using modulators with more pixels or combining multiple modulators.…”

Section: Discussionmentioning

confidence: 99%

Large-scale Ising emulation with four body interaction and all-to-all connections

2020

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Optical Ising machines with two-body interactions have shown potential in solving combinatorial optimization problems which are extremely hard to solve with digital computers. Yet, some physical systems cannot be properly described by only two-body interactions. Here, we propose and demonstrate a nonlinear optics approach to emulate Ising machines containing many spins (up to a million in the absence of optical imperfections) and with tailored all-to-all two and four-body interactions. Our approach employs a spatial light modulator to encode and control the spins in the form of the binary-phase values, and emulates the high-order interaction with frequency conversion in a nonlinear crystal. By implementing adaptive feedback, the system can be evolved into effective spin configurations that well-approximate the ground-states of Ising Hamiltonians with all-to-all connected many-body interactions. Our technique could serve as a tool to probe complex, many-body physics and give rise to exciting applications in big-data optimization, computing, and analytics.

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“…As previously mentioned, DMDs o®er higher switching speed as compared to conventional devices. Smolyaninov et al 91 demonstrated 2D control of free space optical¯elds at 1 GHz modulation speed using DMD operating together with near-¯eld interactions using an electrooptic SPR e®ect. The innovative feature of the work lies in the use a high (2) dielectric thin¯lm as the active layer in a programmable plasmonic phase modulator (PPPM) array, which radically reduces the response time of the electronics addressing the transducer.…”

Section: Application Of Dmd In Sprmentioning

confidence: 99%

Application of digital micromirror devices (DMD) in biomedical instruments

Zhuang

2020

J. Innov. Opt. Health Sci.

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There is an ongoing technological revolution in the field of biomedical instruments. Consequently, high performance healthcare devices have led to remarkable economic developments in the medical hardware industry. Until now, nearly all optical bio-imaging systems are based on the 2-dimensional imaging chip architecture. In fact, recent developments in digital micromirror devices (DMDs) are gradually making their way from conventional optical projection displays into biomedical instruments. As an ultrahigh-speed spatial light modulator, the DMD may offer a range of new applications including real-time biomedical sensing or imaging, as well as orientation tracking and targeted screening. Given its short history, the use of DMD in biomedical and healthcare instruments has emerged only within the past decade. In this paper, we first provide an overview by summarizing all reported cases found in the literature. We then critically analyze the general pros and cons of using DMD, specifically in terms of response speed, stability, accuracy, repeatability, robustness, and degree of automation, in relation to the performance outcome of the designated instrument. Particularly, we shall focus our discussion on the use of Micro-Electro-Mechanical System (MEMS)-based devices in a set of representative instruments including the surface plasmon resonance biosensor, optical microscopes, Raman spectrometers, ophthalmoscopes, and the micro stereolithographic system. Finally, the prospects of using the DMD approach in biomedical or healthcare systems and possible next generation DMD-based biomedical devices are presented.

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Programmable plasmonic phase modulation of free-space wavefronts at gigahertz rates

Cited by 60 publications

References 37 publications

Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection

Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection

Large-scale Ising emulation with four body interaction and all-to-all connections

Application of digital micromirror devices (DMD) in biomedical instruments

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