Prognostische Bedeutung einer Diabeteserkrankung beim Endometriumkarzinom

Steiner, Eric; Eicher, O; Hofmann, Marie‐Claude; W, Weikel; Schmidt, M; Pilch, H; Pg, Knapstein

doi:10.1055/s-2001-19515

Zentralbl Gynakol

2001

DOI: 10.1055/s-2001-19515

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Prognostische Bedeutung einer Diabeteserkrankung beim Endometriumkarzinom

Eric Steiner

O Eicher²,

Marie‐Claude Hofmann³

et al.

Abstract: Our results show a correlation between Diabetes mellitus and adverse prognostic factors witch affects by the rate of lymphonode spread and overall survival.

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“…Endometrial Carcinoma is often associated with medical disorders such as hyperten-sion, diabetes mellitus, obesity, PCOS, and infertility 17,18. Steiner et al,19 found 21.8% of…”

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confidence: 97%

Prognostic factors in endometrial cancer

Bajracharya

Juan

2013

Journal of Institute of Medicine

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Introduction: Endometrial cancer (EC) is the most common malignancy of the female genital tract. It is now the fourth most common gynecological cancer among women and the sixth worldwide cancer in Western countries. It is the most curable of the 10 most common cancers in women and the most frequent and curable of the gynecologic cancers. The incidence is increasing when life expectancy rise. This study was carried out to evaluate the prognostic factors of Endometrial Cancer. Methods: Clinico-pathological characteristics and follow-up cases of endometrial cancer were analysed retrospectively between January 2000 to December 2007 with its prognostic factors influence were statistically analysed. Results: During the study period total 180 patients were taken. Univariate model revealed that the menopausal status, the FIGO stage, grade, histological type, myometrial invasion, ER, PR, peritoneal cytology, lymph node metastases, adjuvant therapy, and the method of operation were related with the prognosis significantly. The multivariate analysis Cox proportion hazards regression model showed that the ER (P=0.004), PR (P=0.000), myometrial invasion (P=0.006) and lymph node metastases (P=0.049) were related with the prognosis significantly. Conclusion: The clinico-pathological character of endometrial cancer is responsible for patient’s better survival. If the patients had early detection and treated in proper modalities, this might improve the good prognosis. DOI: http://dx.doi.org/10.2126/joim.v35i1.8891 Journal of Institute of Medicine, April, 2013; 35:9-17

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“…Endometrial Carcinoma is often associated with medical disorders such as hyperten-sion, diabetes mellitus, obesity, PCOS, and infertility 17,18. Steiner et al,19 found 21.8% of…”

mentioning

confidence: 97%

Prognostic factors in endometrial cancer

Bajracharya

Juan

2013

Journal of Institute of Medicine

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Carcinoma de endometrio. Utilidad de la resonancia magnética nuclear en la estadificación prequirúrgica

Higuera

Sáez

Pérez

et al. 2004

Clínica e Investigación en Ginecología y Obstetricia

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Primary clinical analysis of medical disorders in Chinese women with endometrial carcinoma

Wang¹,

Wang²,

Wei³

2004

Int J Gynecol Cancer

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The objectives of this study were to survey the prevalence of medical disorders in Chinese women with endometrial carcinoma and evaluate their potential impact on the clinical treatment and prognosis. Three hundred and seven women with endometrial carcinoma, from July 1, 1971 to October 31, 2001, were analyzed retrospectively. One hundred and forty-six of them (47.6%) were found to have associated medical disorders. The most common medical disorders were hypertension (33.9%), diabetes mellitus (9.8%), and coronary heart disease (9.4%). As many as 38.4% of the women had two or more medical disorders. The patients with medical disorders were on average elder than those without any medical disorders (P < 0.01). Radiotherapy and chemotherapy were administered more commonly in the group with medical disorders than in the one without (P < 0.01). The rate of surgical procedures was significantly lower in the group with medical disorders than in the group without (P < 0.01). However, the extent of surgical interventions was similar in both groups (P > 0.05). The occurrence of medical disorders was independent of the tumor stage, grade, and histological types (P > 0.05). In addition, follow-up data showed that the 3-year and 5-year survivals were not influenced by the medical disorders (P > 0.05). The results thus suggest that Chinese women with endometrial carcinoma have frequently concurrent medical disorders. Selection of treatment strategies can be influenced by these associated medical disorders, but the overall survival is little changed.

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Prognostische Bedeutung einer Diabeteserkrankung beim Endometriumkarzinom

Abstract: Our results show a correlation between Diabetes mellitus and adverse prognostic factors witch affects by the rate of lymphonode spread and overall survival.

Cited by 5 publications

References 1 publication

Prognostic factors in endometrial cancer

Prognostic factors in endometrial cancer

Carcinoma de endometrio. Utilidad de la resonancia magnética nuclear en la estadificación prequirúrgica

Primary clinical analysis of medical disorders in Chinese women with endometrial carcinoma

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