Prognostic Variables of Papillary Thyroid Carcinomas with Local Invasion.

Abstract

Abstract.To In conclusion, the survival rate of the ETE of papillary thyroid cancer was lower when compared with stage I, especially in older male patients with higher post-operative serum Tg levels.

Number of central lymph node metastasis for predicting lateral lymph node metastasis in papillary thyroid microcarcinoma

“…We used multivariate logistic regression analysis to confirm the independently predictive value of number of positive central lymph node ≥2 for lateral lymph node metastasis. The age at diagnosis, sex, and tumor size are associated with the clinical outcomes in thyroid cancer . After adjusting for the established clinicopathological prognostic factors and the remaining statistically significant factors, the number of positive central lymph nodes ≥2, underlying Hashimoto thyroiditis, and extrathyroidal extension were found to be the independent predictive factors for lateral lymph node metastasis with ORs of 11.282, 4.340, and 2.838, respectively ( p < .05).…”

“…The age at diagnosis, sex, and tumor size are associated with the clinical outcomes in thyroid cancer. [11][12][13] After adjusting for the established clinicopathological prognostic factors and the remaining statistically significant factors, the number of positive central lymph nodes 2, underlying Hashimoto thyroiditis, and extrathyroidal extension were found to be the independent predictive factors for lateral lymph node metastasis with ORs of 11.282, 4.340, and 2.838, respectively (p < .05). The number of positive central lymph nodes 2 may strongly predict the presence of lateral lymph node metastasis based on a significantly high OR.…”

Sex is not an independent risk factor for survival in differentiated thyroid cancer

“…Sex alone, however, did not impact patient survival in this study. Men have also been found to have higher rates of stage III and IV disease, greater tendency for distant metastases, and more advanced local disease leading to less complete tumor resection and a higher rate of recurrence …”

Minimal Extrathyroid Extension Does Not Affect the Relapse-Free Survival of Patients with Papillary Thyroid Carcinoma Measuring 4 cm or Less over the Age of 45 Years

“…[3][4][5][6][7][8] However, all of these studies investigated the difference in prognosis between patients with and without extrathyroid extension without considering differences in the degree of extension.…”