Abstract:Background
Successful engraftment of human cancer biopsies in immunodeficient mice correlates with the poor prognosis of patients. This was reported 30 years ago for children with neuroblastoma, but the standard of care treatment evolved significantly during the last 15 years, leading to improved survival of these patients. Here, we evaluated the association of patient‐derived xenograft (PDX) engraftment and prognosis in patients receiving up‐to‐date treatments for cancers classified as metastatic (stage M) hi… Show more
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