Abstract:Introduction Use of fractional exhaled nitric oxide (FeNO) is recommended for asthma diagnosis but its role in guiding safe reduction of inhaled corticosteroids (ICS) is unclear. Aims and objectives To assess the value of FeNO in identifying asthma patients in whom ICS can be safely reduced. Methods We performed a systematic electronic database search to identify studies which recruited asthma patients aged >=12 years maintained on low to moderate dose ICS in whom FeNO was measured at baseline before subsequen… Show more
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