Prognostic Value of Tumor-to-Blood Standardized Uptake Ratio in Patients with Resectable Non-Small-Cell Lung Cancer

Abstract

Among PET parameters, SUR was the independent predictor of recurrence in NSCLC patients who received curative surgery. N stage was the independent prognostic factor for both recurrence and death. Both parameters could be used to stratify the risk of NSCLC patients.

Improving the Prognostic Performance of SUVmax in 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Using Tumor-to-Liver and Tumor-to-Blood Standard Uptake Ratio for Locally Advanced Cervical Cancer Treated with Concurrent Chemoradiotherapy

“…Among various metabolic parameters, the tSUV max normalized to liver uptake after neoadjuvant chemotherapy was the best predictor of a pathologic complete response in locally advanced rectal cancer [13]. Moreover, the standardized uptake TBR was an independent predictor of recurrence in non-small-cell lung cancer [14]. In our study, tSUV max had no significant impact in predicting tumor recurrence or death.…”

“…The liver and blood pool are the most widely used references because they maintain a nearly constant SUV level over time following the injection of 18 F-FDG [ 12 , 13 ]. Recent studies have shown that the tumor-to–normal liver SUV ratio (TLR) and tumor-to–blood pool SUV ratio (TBR) are independent prognostic factors in several cancers [ 13 , 14 ]. However, the prognostic roles of the normalization of SUV max to the liver or blood pool have not been reported previously in cervical cancer.…”

Test–Retest Variability in Lesion SUV and Lesion SUR in 18F-FDG PET: An Analysis of Data from Two Prospective Multicenter Trials

“…Although uptake time variability has already been recognized as possibly contributing to SUV TRV (11), variability in arterial blood SUV does not yet seem to have been considered. More importantly, if our assumption is correct, the recently introduced uptake time-corrected tumor-to-blood SUV ratio (SUR) (15,16) would represent a means of quantitatively accounting for these two sources of TRV and should therefore exhibit a lower TRV than SUV (which in turn could explain the superiority of SUR over SUV regarding prognostic value as demonstrated in initial clinical studies (17)(18)(19)). The purpose of the present study was to compare the TRV of both uptake measures.…”

‘Virtual experience’ as an intervention before a positron emission tomography/CT scan may ease patients’ anxiety and improve image quality

“…Due to these advantages, it has a critical role in the diagnostic investigation, cancer staging, recurrence detection, therapy response evaluation and prognosis prediction of many different kinds of tumours. [1][2][3][4] An increasing number of cancer patients are required to undergo PET/CT examination. However, many studies have demonstrated that patients experienced a high level of anxiety during PET/CT examination because of a variety of reasons, 5,6 such as the use of radiopharmaceuticals and uncertain of the scan results.…”

“…Positron emission tomography/computer tomography (PET/CT) is a whole‐body, combined‐modality functional imaging technique. Due to these advantages, it has a critical role in the diagnostic investigation, cancer staging, recurrence detection, therapy response evaluation and prognosis prediction of many different kinds of tumours 1–4 . An increasing number of cancer patients are required to undergo PET/CT examination.…”