2018
DOI: 10.21873/anticanres.12834
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Prognostic Value of Serum Creatinine Levels in Patients with Epithelial Ovarian Cancer

Abstract: The preoperative serum level of creatinine may be useful as an additional independent prognostic parameter in patients with EOC.

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Cited by 20 publications
(19 citation statements)
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“…Although biomarkers associated with OS in patients with CRC may be moderately predictive of survival, additional research and evaluation are needed to improve their predictive utility (18)(19)(20)(21). In this study, we evaluated association between Scr levels and OS in patients with CRC because Scr has been reported to be predictive of prognosis in many cancers (8)(9)(10)(11). Our study revealed a correlation between Scr concentrations and OS in patients with CRC, which was consistent with previous studies in other cancers.…”
Section: Discussionsupporting
confidence: 88%
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“…Although biomarkers associated with OS in patients with CRC may be moderately predictive of survival, additional research and evaluation are needed to improve their predictive utility (18)(19)(20)(21). In this study, we evaluated association between Scr levels and OS in patients with CRC because Scr has been reported to be predictive of prognosis in many cancers (8)(9)(10)(11). Our study revealed a correlation between Scr concentrations and OS in patients with CRC, which was consistent with previous studies in other cancers.…”
Section: Discussionsupporting
confidence: 88%
“…Willegger et al studied 132 patients undergoing sarcoma resection and found that Scr could be used as a predictive biomarker for disease-specific outcomes in myofibroblastic and fibroblastic sarcomas (8). In a retrospective cohort study, Scr was an independent predictor of overall survival (OS) in 498 patients with primary epithelial ovarian cancer (9). Z ̇yczkowski et al found that Scr may be useful for estimating the 5-year survival of patients with renal cell carcinoma (10).…”
Section: Introductionmentioning
confidence: 99%
“…KIF20A overexpression predicted unfavorable clinical outcome and had potential to serve as a useful prognostic biomarker for epithelial OC patients [13]. The high preoperative serum level of Creatinine was associated with poor survival, which indicated that it might be an additional independent prognostic parameter in patients with epithelial OC [14]. Nucleus and/or cytoplasm of β-catenin expression might be associated with tumor progression and subsequently represent a predictive factor of poor prognosis in OC patients [15].…”
Section: Discussionmentioning
confidence: 99%
“…Because of the absence of early symptoms and lack of an effective screening option, the majority of epithelial ovarian cancer (EOC) cases are diagnosed at an advanced stage. Various prognostic parameters have been evaluated for ovarian cancer, but none of them have entered clinical practice to date 2 , 3 , 4 , 5 .…”
Section: Introductionmentioning
confidence: 99%