Prognostic value of low and high ankle-brachial index in hospitalized medical patients

Pasqualini, Leonella; Schillaci, Giuseppe; Pirro, Matteo; Vaudo, Gaetano; Leli, Christian; Colella, Renato; Innocente, Salvatore; Ciuffetti, Giovańni; Mannarino, Elmo

doi:10.1016/j.ejim.2011.09.004

Cited by 28 publications

(28 citation statements)

References 32 publications

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“…And the overweight participants with larger ABI value were susceptible to HCHD. Some studies proved that high ABI was independently associated with increased CVD risk [4]–[6]. Otherwise, the Atherosclerosis Risk in Communities (ARIC) Study found that white and black men and women with high ABI did not have higher CVD event rates than those with normal ABI [7].…”

Section: Discussionmentioning

confidence: 99%

“…The Strong Heart Study(SHS) was the first large prospective study to show that the American Indians with high ABI had increased all-cause and cardiovascular disease (CVD) mortality [4]. Other study evidence also demonstrated that high ABI was independently associated with incident CVD events defined as coronary disease, stroke, or other atherosclerotic CVD death [5], [6]. However, the Atherosclerosis Risk in Communities (ARIC) Study did not support this conclusion and showed that white and black men and women with high ABI did not suffer greater CVD event rates than those with normal ABI [7].…”

Section: Introductionmentioning

confidence: 99%

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Combination of High Ankle–Brachial Index and Hard Coronary Heart Disease Framingham Risk Score in Predicting the Risk of Ischemic Stroke in General Population

et al. 2014

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Our previous study showed that the patients with more metabolic risk factors had higher risk of high ankle–brachial index (ABI), but the relationship between high ABI and the risk of severe cardiovascular and cerebrovascular diseases is still under debate. This study aims to evaluate this association in the general population. 1486 subjects of South China were recruited in the study. 61 subjects were defined as high ABI group (ABI≥1.3) and 65 subjects were randomly selected as normal ABI group (0.9

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Combination of High Ankle–Brachial Index and Hard Coronary Heart Disease Framingham Risk Score in Predicting the Risk of Ischemic Stroke in General Population

et al. 2014

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“…And high ABI was associated with the elevated morbidity of CVD 5, 6. Furthermore, high ABI was shown to have a close relationship with all-cause mortality 1, 4.…”

Section: Discussionmentioning

confidence: 91%

“…And other studies confirmed that high ABI was a significant predictor of high cardiovascular mortality and all-cause mortality in patients on hemodialysis 2-4. Pasqualini et al also suggested that high ABI was independently associated with cardiovascular mortality and predicted all-cause mortality in hospitalized medical patients 5. Furthermore, Bouthi et al demonstrated that high ABI may be strongly associated with the prevalent of silent cerebral infarction in Japanese patients with type 2 diabetes 6.…”

Section: Introductionmentioning

confidence: 89%

Inflammation and Oxidative Stress are Associated with the Prevalence of High Aankle-brachial Index in Metabolic Syndrome Patients without Chronic Renal Failure

Zhang¹,

Chen²,

Zhang³

et al. 2013

Int. J. Med. Sci.

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Aims: High ankle-brachial index (ABI) is marker of increased cardiovascular morbidity and mortality, while the relationship and mechanism between high ABI and metabolic syndrome (MetS) are unclear. The objectives of this study were to determine the relationship and possible mechanism of MetS with high ABI.Methods: 341 participants without CRF were recruited. Among these participants, 58 participants (ABI ≥ 1.3) were include in high ABI group and the other 283 participants (0.9 < ABI < 1.3) were include in normal ABI group. Furthermore, these 341 participants were also divided into MetS group (n = 54) and non-MetS group (n = 287). All participants received examinations including body mass index (BMI), ABI and related biochemical parameters.Results: Compared with non-MetS group, the prevalence of high ABI was higher in MetS group (27.8% vs. 15%, p < 0.05). Participants with 3-4 metabolic risk factors had higher prevalence of high ABI than those with 0-1 metabolic risk factors (27.8% vs. 12.7%, p < 0.05). The prevalence of high ABI in overweight participants was higher than those with normal body weight. And the participants with hypertension also had higher prevalence of high ABI than normotensive participants. BMI, high-sensitivity C-reactive protein (hsCRP) and superoxide dismutase (SOD) were all higher in high ABI group than normal ABI group (p < 0.05).Conclusions: More metabolic risk factors have increased the risk of high ABI. Inflammation and oxidative stress are associated with prevalence of high ABI in metabolic syndrome patients without chronic renal failure.

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“…A 36% prevalence of low ABI has been described when ABI was measured by pulse palpation [12]. Hand held Doppler measurements recently showed a 29 % PAD prevalence [13], similar to that observed among patients hospitalised for acute coronary and cerebrovascular events [14,15], and in those hospitalised for non-vascular causes in a tertiary care hospital [16].…”

Section: Introductionmentioning

confidence: 95%

Accuracy of in-patients ankle-brachial index measurement by medical students

Monti

Calanca

Alatri

et al. 2016

Vasa

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Summary:Background: Ankle brachial index (ABI) is a fi rst line non-invasive screening tool for peripheral arterial disease (PAD) in at risk populations. The need to extend ABI use in large population screening has urged its use by professionals other than vascular physicians. As advocated by the American Heart Association, ABI teaching is part of medical curriculum in several countries. We determine accuracy in ABI measurement by trained medical students compared with an experienced angiologist. Methods: Twelve 6th year medical students underwent 9 days of training at Lausanne University Hospital. Students and an experienced angiologist, blinded to students' results, screened consecutive hospitalised patients aged ≥ 65 or ≥ 50 with at least one cardiovascular risk factor during a 6-week period. Results: A total of 249 patients were screened of whom 59 (23.7 %) met the inclusion criteria. Median age was 80, 45.8 % were women, and 6.8 % were symptomatic. In total, 116 ABIs were available for analysis. Agreement between students and angiologist was moderate with a k-value of 0.498 (95 % confi dence interval: 0.389 -0.606). Overall accuracy and precision of PAD screening performed by students showed sensitivity of 73.2 % and specifi city of 88.0 %. Positive and negative predictive values were 76.9 % and 85.7 %, respectively; positive and negative likelihood ratios were 6.3 and 3, respectively. Conclusions: A nine day training program on ABI measurement is not suffi cient for inexperienced medical students to achieve an acceptable diagnostic accuracy in detecting PAD in at risk populations.

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Prognostic value of low and high ankle-brachial index in hospitalized medical patients

Cited by 28 publications

References 32 publications

Combination of High Ankle–Brachial Index and Hard Coronary Heart Disease Framingham Risk Score in Predicting the Risk of Ischemic Stroke in General Population

Combination of High Ankle–Brachial Index and Hard Coronary Heart Disease Framingham Risk Score in Predicting the Risk of Ischemic Stroke in General Population

Inflammation and Oxidative Stress are Associated with the Prevalence of High Aankle-brachial Index in Metabolic Syndrome Patients without Chronic Renal Failure

Accuracy of in-patients ankle-brachial index measurement by medical students

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