Prognostic Value of Intraoperative Blood-Flow Measurements in Femoropopliteal Bypass Vein-Grafts

Little, J. M.; Sheil, A. G. R.; Loewenthal, John; Goodman, A. H.

doi:10.1016/s0140-6736(68)92503-8

Cited by 35 publications

(10 citation statements)

References 8 publications

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“…Some authors have not found graft flows to be of predictive value (Mundt et al, 1969;Barner et al, 1974), whereas others have found a correlation between intraoperative flow rates and clinical outcome (Little et al, 1968;Terry, Allan & Taylor, 1972;Dedichen, 1973). The latter authors, however, have different operative techniques, and this makes the assess-Scand J Thor Cardiovnsc Surg 14 ment of results difficult.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, only 40 out of 90 patients reported by Dedichen (1973) were treated with a reversed femoropopliteal vein bypass graft, while the remaining 50 patients underwent a semiclosed thrombendarterectomy . In the study presented by Little et al (1968) comprising 40 patients, both reversed and in situ grafts were used. Amongst 80 limb reconstructions reported by Terry, Allan & Taylor (1972), 43 were femoropopliteal reversed vein bypass grafts.…”

Section: Discussionmentioning

confidence: 99%

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Intra-Operative Graft Blood Flow Related to Failure of Femoro-Popliteal Bypass Grafts

Sonnenfeld

Cronestrand

1980

Scandinavian Journal of Thoracic and Cardiovascular Surgery

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The prognostic significance of intra-operative blood flow, as measured by electromagnetic flowmetry, was investigated in 127 limbs, which were operated on with a reversed femoropopliteal saphenous vein bypass graft because of symptomatic atherosclerotic occlusion of the superficial femoral artery. Thromboses occurring in the first postoperative month are defined as early failures and thereafter as late failures. There were three early graft failures. The basal and augmented flow rates during pharmacological vasodilation of these grafts were less than half those of the grafts remaining patent. Eight additional late graft occlusions occurred. Whereas the basal blood flow of these grafts did not differ significantly from that of the grafts which remained patent, the maximal flow rate was significantly lower (p less than 0.05). The overall incidence of graft failure at basal and maximal flow rates of 100 ml/min or less and 150 ml/min or less, respectively, was 35%, while, at higher flow rates, this incidence was reduced to 5% (p less than 0.001). This study emphasizes that intra-operative femoropopliteal vein graft flow provides prognostic indications of graft failure.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Intra-Operative Graft Blood Flow Related to Failure of Femoro-Popliteal Bypass Grafts

Sonnenfeld

Cronestrand

1980

Scandinavian Journal of Thoracic and Cardiovascular Surgery

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“…The relationship between intraoperative basal graft flow, response to papaverine augmentation, and incidence of subsequent graft thrombosis has been evaluated by several investigators. Eighty percent of grafts with flows less than 60 ml/min failed within three months in the series of Little et al 15 Although Terry and his associates16 showed a higher frequency of graft thrombosis if the flow was less than 100 ml/min (54%), two of four grafts with flows less than 50 ml/min remained patent. Mannick et al17 studied 14 grafts and described one bypass that re¬ mained patent with a basal flow of only 15 ml/min.…”

Section: Intraoperative Flowmentioning

confidence: 96%

Prognostic Indicators in Femoropopliteal Reconstructions

Dean¹

1975

Arch Surg

100

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“…However, there are also several authors whose conclusions on graft patency are either directly or indirectly related to fluid mechanics. Little et al(1968), as a result of a study of forty saphenous vein by-pass grafts, found that patency improves with increasing intra-operative graft flow. General agreement with Little et al is provided by Golding et a1 (1966) and Cappelen et al(l967).…”

Section: Factors Affecting Graft Patencymentioning

confidence: 99%

The Flow in Idealized Models of the Femoro-Popliteal By-Pass Graft

Taylor¹,

Ashton²,

Foster³

1978

Engineering in Medicine

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The factors affecting graft patency are first introduced and a miniature model of a by-pass graft junction is described. The flow conditions in the model were established by appropriate modelling criteria and the flow was visualized under both steady and pulsating conditions by using as the working fluid anticoagulated plasma plus a few red cells. Qualitative results are described. By neutralizing the anticoagulant some insight into the clotting process was obtained. Experimental work on a large scale, two-dimensional models, together with relevant theoretical predictions, aimed at evaluating the distribution of wall shear stress around a junction are also described.

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Prognostic Value of Intraoperative Blood-Flow Measurements in Femoropopliteal Bypass Vein-Grafts

Cited by 35 publications

References 8 publications

Intra-Operative Graft Blood Flow Related to Failure of Femoro-Popliteal Bypass Grafts

Intra-Operative Graft Blood Flow Related to Failure of Femoro-Popliteal Bypass Grafts

Prognostic Indicators in Femoropopliteal Reconstructions

The Flow in Idealized Models of the Femoro-Popliteal By-Pass Graft

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