Prognostic value of inducible myocardial ischemia in predicting cardiovascular events after renal transplantation

Dussol, Bertrand; Bonnet, Jean‐Louis; Sampol, J.; Savin, Bernard; Forte, Catherine De La; Mundler, O.; Habib, Gilbert; Morange, Sophie; Barrau, K.; Loundoun, Anderson; Vacher-Coponat, Henri; Berland, Yvon

doi:10.1111/j.1523-1755.2004.00929.x

Cited by 20 publications

(7 citation statements)

References 32 publications

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“…Inducible myocardial ischemia was seen in 10% of the patients and was associated with increased future events. 10 These series are limited to patients with advanced renal impairment and are limited by small numbers and small number of events. Our study is also in agreement with a recently published analysis that evaluated the prognostic value of dobutamine stress echo among the entire strata of renal function in 2292 patients.…”

Section: Al-mallah Et Al Myocardial Perfusion Imaging and Renal Functionmentioning

confidence: 99%

Incremental Prognostic Value of Myocardial Perfusion Imaging in Patients Referred to Stress Single-Photon Emission Computed Tomography With Renal Dysfunction

Al-Mallah

Hachamovitch

Dorbala

et al. 2009

Circ: Cardiovascular Imaging

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Background-Coronary artery disease is the main cause of mortality and morbidity in patients with impaired renal function. The aim of this study was to evaluate the prognostic implications of single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) in patients with impaired renal function. Methods and Results-We included 7348 consecutive patients (mean age, 64Ϯ13 years; 51% men) referred for SPECT-MPI between March 2002 and October 2006. Renal function was estimated using the estimated glomerular filtration rate formula. Patients were followed up for the incidence of all-cause mortality. Patients with decreased glomerular filtration rate were more often older, with higher prevalence of conventional risk factors (PϽ0.001). After a median follow-up of 2.6 years (25th to 75th percentiles, 1.5 to 3.7), 693 (9.4%) patients died. The risk of death increased with worsening kidney function. At each stage of impaired renal function, patients with abnormal SPECT-MPI had increased hazard of adverse events (PϽ0.0001). Using Cox proportional hazards analysis, the magnitude of total perfusion deficit and ischemia on MPI were associated with worse outcome after adjusting for confounding variables including glomerular filtration rate and ejection fraction. Conclusions-SPECT-MPI

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Section: Al-mallah Et Al Myocardial Perfusion Imaging and Renal Functionmentioning

confidence: 99%

Incremental Prognostic Value of Myocardial Perfusion Imaging in Patients Referred to Stress Single-Photon Emission Computed Tomography With Renal Dysfunction

Al-Mallah

Hachamovitch

Dorbala

et al. 2009

Circ: Cardiovascular Imaging

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“…Previous studies showed that DSE might be useful in predicting prognosis in patients with CKD and renal transplantation recipients [36][37][38][39][40]. The largest study evaluating the prognostic value of DSE was among 485 patients with CKD in a study of Bergeron et al According to the data of this study, both ECG and echocardiographic evidence of stress-induced ischemia and the percentage of ischemic segments during DSE were strong independent predictors of mortality, even in patients who subsequently underwent renal transplantation [41].…”

Section: Stress Testsmentioning

confidence: 67%

Cardiovascular Evaluation of Renal Transplant Recipients

Gülmez¹

2017

J Clin Exp Cardiolog

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Cardiovascular disease (CVD) is one of the major causes of death among renal transplant recipients. Moreover, several prospective studies among renal transplant recipients showed that increased incidence of CVD is still present after transplantation. Therefore, evaluation for the presence of CVD before transplantation is strongly advised. Although several screening tests are used for the detection of CVD, the relative performance of these tests for coronary artery disease (CAD) is uncertain. This review discusses the definition, risk factors, epidemiology, and the most used screening tests that might help cardiologists in providing information about the diagnosis and risk stratification before renal transplantation.

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“…59 More importantly, perfusion abnormalities by RMPI have been consistently found to predict adverse cardiac events in these asymptomatic CKD patients. [56][57][58][59][60] In summary, asymptomatic subjects with CKD have an intermediate likelihood of having occult CAD, and RMPI has been shown to have excellent diagnostic accuracy and independent prognostic value in these patients. However, the comparative effectiveness and cost-effectiveness of RMPI in asymptomatic subjects with CKD is unknown.…”

Section: Chronic Kidney Diseasementioning

confidence: 99%

The role of radionuclide myocardial perfusion imaging for asymptomatic individuals

Hendel

Abbott

Bateman

et al. 2011

Journal of Nuclear Cardiology

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Prognostic value of inducible myocardial ischemia in predicting cardiovascular events after renal transplantation

Abstract: IMI was present in 10% of RTR aged > or =50 years, and was predicted by acute rejection and left ventricular hypertrophy. IMI had a strong effect on major cardiovascular events in this population.

Cited by 20 publications

References 32 publications

Incremental Prognostic Value of Myocardial Perfusion Imaging in Patients Referred to Stress Single-Photon Emission Computed Tomography With Renal Dysfunction

Incremental Prognostic Value of Myocardial Perfusion Imaging in Patients Referred to Stress Single-Photon Emission Computed Tomography With Renal Dysfunction

Cardiovascular Evaluation of Renal Transplant Recipients

The role of radionuclide myocardial perfusion imaging for asymptomatic individuals

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