Prognostic Value of Coronary Artery Calcium Score for Determination of Presence and Severity of Coronary Artery Disease

Moradi, Maryam; Nouri, Shadi; Nourozi, Ali; Golbidi, Danial

doi:10.12659/pjr.900643

Cited by 11 publications

(5 citation statements)

References 23 publications

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“…In our study, the mean calcium score among participants was 382.45 ± 47.5 and the patients were classified as normal, minimal, mild, moderate and severe calcium scores. We found that the mean calcium score was significantly higher in patients with severe CAD (P<0.001).This was in agreement with Moradi M et al [15]. Also Almasi et al evaluated the value of CACS for predicting the presence and severity of CAD among 202 patients.…”

Section: Discussionsupporting

confidence: 91%

Vitamin D Levels Assessment in Relation to Coronary MDCT Angiographic Findings

Tantawy¹,

Hasanin

Farid

2019

Zagazig University Medical Journal

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Background: Although vitamin D has a major role at the skeletal mineralization, it has been implicated at cardio vascular system, owing to abundance of its receptor there. Atherosclerosis is the most presenting symptom of the cardio-vascular system that warrants the urge to detect the effect of vitamin D serum level changes in progression of the atherosclerosis. Objective is to assess the correlation between vitamin D level and coronary artery findings using MDCT. Methods: Two hundred and Fifty patients were included in our study, all of them underwent MDCT for coronary artery angiography, and then the findings were compared with vitamin D serum levels. Results: 4 % of all examined patients (n=10) had vitamin D deficiency, 44 % (n=110) had insufficient levels of vitamin D, 52 % have sufficient vitamin D level (n=130). There is significant positive correlation between Lab. vitamin D levels and coronary artery calcium score (CACS) with P<0.005. Conclusions: Vitamin D levels play significant role in modifying the risk of coronary artery involvement.

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Section: Discussionsupporting

confidence: 91%

Vitamin D Levels Assessment in Relation to Coronary MDCT Angiographic Findings

Tantawy¹,

Hasanin

Farid

2019

Zagazig University Medical Journal

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“…In addition, the average CACS in different CAD groups were compared and found to be in agreement with the findings of another study in a similar population. 31 …”

Section: Discussionmentioning

confidence: 99%

Evaluation of vitamin D levels in relation to coronary CT angiographic findings in an Iranian population

Moradi¹,

Foroutanfar²

2017

VHRM

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BackgroundVitamin D deficiency, as a predisposing factor for coronary artery disease (CAD), is a subject of increasing interest. However, its role as a risk factor has not been proven. This study aimed to investigate the relationship between serum vitamin D levels and CAD.Materials and methodsUsing a cross-sectional design, 180 patients who were candidates for coronary computed tomography angiography (CCTA) were selected. Serum levels of vitamin D were measured and compared with the results of CCTA (including calcium score, and presence and severity of coronary artery involvement due to atherosclerotic plaques).ResultsThe mean age of the participants was 60.5±10.6 years and the mean serum vitamin D level was 26.2±15.9 ng/dL (range, 3.5–83.2 ng/dL). Overall, 6.1% of the participants (n=11) had vitamin D deficiency, 56.1% (n=101) had insufficient levels of vitamin D, and 37.8% (n=68) had sufficient levels of vitamin D. The mean serum vitamin D level was significantly lower in patients with severe CAD (P=0.004). The serum vitamin D level in the “positive for CAD” group was 20.98 ng/mL, significantly lower than the level in the “negative for CAD” group (30.47 ng/mL; P<0.001). The mean calcium score among participants was 533.5±87.9. Based on the Spearman test, a significant negative correlation (−0.21) was detected between the serum vitamin D level and coronary artery calcium score (CACS) (P=0.005). Conversely, the mean CACS in the vitamin D deficient group was significantly higher than in the insufficient and sufficient vitamin D groups (P<0.001 for both comparisons).ConclusionVitamin D deficiency was associated with coronary artery calcification and severity of coronary artery stenosis in Iranian patients.

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“…Te risk probability of developing coronary stenosis ≥50% remained consistent as the CACS increased beyond 230.8. Previous studies have indicated a positive correlation between higher CACS and an increased likelihood of coronary stenosis [24][25][26]. Tis study further suggested that a CACS of 63.6-66 is an infection point for coronary stenosis ≥50%.…”

Section: Discussionmentioning

confidence: 87%

Relationship between Coronary Artery Calcium Score and Coronary Stenosis

Chen,

Zhao,

Cai

et al. 2023

Cardiology Research and Practice

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Background. The coronary artery calcium score (CACS) is commonly employed to quantify the degree of calcification in coronary atherosclerosis. Indeed, increased coronary stenosis severity is associated with a progressive increase in CACS. Objectives. This study sought to explore the association between CACS and coronary stenosis of ≥50% and ≥70%. Methods. We conducted a retrospective analysis of patient data collected between July 1, 2017, and March 3, 2022, at Jiangmen Central Hospital. A total of 208 patients, presenting with both symptomatic and asymptomatic manifestations and suspected coronary artery disease (CAD), were included. Statistical analyses included ROC curve assessments, subgroup analyses based on age, and comparisons of CACS values against the presence of coronary stenosis ≥50% and ≥70%. Results. Ultimately, 208 patients were included, with a median age of 65.0 years and a median CACS of 115.7 (interquartile range: 13.7–369.4). A CACS threshold of ≥1300 demonstrated a specificity of 100% for coronary stenosis of ≥50%. Notably, the percentage of patients with obstructive CAD showing CACS = 0 was significantly higher in those under 65 years (15.1%) compared to patients over 65 years (3.8%) ( P = 0.005 ). The inflection point, at which the risk probability for coronary stenosis of ≥50% shifted from being a protective factor to a risk factor, was observed when CACS fell within the range of 63.3 to 66.0. Conclusion. CACS demonstrates good performance for the detection of coronary artery stenosis.

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Prognostic Value of Coronary Artery Calcium Score for Determination of Presence and Severity of Coronary Artery Disease

Cited by 11 publications

References 23 publications

Vitamin D Levels Assessment in Relation to Coronary MDCT Angiographic Findings

Vitamin D Levels Assessment in Relation to Coronary MDCT Angiographic Findings

Evaluation of vitamin D levels in relation to coronary CT angiographic findings in an Iranian population

Relationship between Coronary Artery Calcium Score and Coronary Stenosis

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