Prognostic value of complete blood count parameters in COVID-19 patients

Demirkol, Muhammed Emin; Kaya, Musa; Kocadağ, Derya; Özsarı, Emine

doi:10.54307/nwmj.2022.62681

Cited by 2 publications

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“…Regarding the hematological parameters, lower hemoglobin levels and higher TLC were associated with mortality because of marked disease severity coinciding with other studies [31,32].…”

Section: Discussionsupporting

confidence: 89%

Blood Urea Nitrogen to Albumin Ratio is a Predictor of Mortality among Hospitalized Geriatric Patients with COVID-19.

al.¹

2022

The Egyptian Journal of Geriatrics and Gerontology

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Aim: This study aims to determine predictors of mortality among hospitalized geriatric patients with COVID-19 with a particular concern about the predictive value of blood urea nitrogen to albumin ratio (BAR). Methods: A retrospective cohort study included 114 geriatric patients (aged ≥ 60 years) admitted to a geriatrics hospital for isolation. A review of the medical files of participants was conducted to extract data regarding age, sex, comorbidities, clinical manifestations of COVID-19 and laboratory data including haematology, biochemistry and inflammatory markers on admission. BAR and Charlson comorbidity index (CCI) were calculated. The primary outcome was in-hospital mortality. Appropriate statistical analyses were operated. RESULTS: 59 (51.8%) patients died at the hospital. Comorbidities associated with mortality included diabetes mellitus, old stroke, hypertension, and cardiac disease besides higher CCI. Reporting of fever, fatigue, sore throat and delirium /altered mental status were also associated with mortality. Significant biomarkers included lower hemoglobin and serum albumin, higher total leukocyte count, serum creatinine, blood urea nitrogen, lactate dehydrogenase, D-dimer, c-reactive protein (CRP) and BAR. BAR at a cutoff of 12.92 mg/gm had the best predictive performance for mortality. Serum BAR > 12.92 mg/gm, albumin < 3.05 g/dl and CRP > 108 mg/l were independent predictors of in-hospital mortality CONCLUSION: Serum BAR > 12.92 mg/gm, albumin < 3.05 g/dl and CRP > 108 mg/l are independent predictors of mortality among hospitalized geriatric patients with COVID-19. BAR is a convenient biomarker and has the best predictive performance to early pick up COVID-19 geriatric patients at high risk of mortality.

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“…Regarding the hematological parameters, lower hemoglobin levels and higher TLC were associated with mortality because of marked disease severity coinciding with other studies [31,32].…”

Section: Discussionsupporting

confidence: 89%

Blood Urea Nitrogen to Albumin Ratio is a Predictor of Mortality among Hospitalized Geriatric Patients with COVID-19.

al.¹

2022

The Egyptian Journal of Geriatrics and Gerontology

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Revisiting the COVID-19 Pandemic: Mortality and Predictors of Death in Adult Patients in the Intensive Care Unit

Sousa Neto,

Mendes-Rodrigues,

Pedroso

et al. 2024

Life

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COVID-19 has generated a global impact due to its contagiousness and high lethality rates, with a large number of deaths occurring in intensive care units (ICUs). This study aimed to verify the occurrence of and understand the factors related to mortality in adult patients with COVID-19 admitted to the ICU in a tertiary hospital. This is a retrospective cohort study, which included COVID-19 patients admitted between March 2020 and December 2021. A total of 588 patients were included, of whom the majority (55.27%) did not survive. Invasive mechanical ventilation was the strongest predictor of the risk of death in the ICU with OR = 97.85 (95% CI = 39.10–244.86; p < 0.001), along with age and Simplified Acute Physiology Score 3 (SAPS3). The length of the ICU stay was protective. Evaluating patients on invasive mechanical ventilation in isolation, using an adjusted model, we found the following risk factors: use of vasopressin, renal replacement therapy, red cell distribution width > 15, use of hydrocortisone, and age in years. Protective factors included the days of mechanical ventilation use, being admitted from another service, and being of female sex. Identifying early predictors of mortality in patients with COVID-19 who require hospitalization is essential in the search for actions to prevent and manage complications, which can increase the survival of these patients and reduce the impact on health services.

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Prognostic value of complete blood count parameters in COVID-19 patients

Cited by 2 publications

References 0 publications

Blood Urea Nitrogen to Albumin Ratio is a Predictor of Mortality among Hospitalized Geriatric Patients with COVID-19.

Blood Urea Nitrogen to Albumin Ratio is a Predictor of Mortality among Hospitalized Geriatric Patients with COVID-19.

Revisiting the COVID-19 Pandemic: Mortality and Predictors of Death in Adult Patients in the Intensive Care Unit

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