Prognostic Value of Anatomical SYNTAX Score and SYNTAX Score II in Veterans With Left Main and/or Three-Vessel Coronary Artery Disease

Misumida, Naoki; Ahmed, Ahmed Elsharawy; Barlow, Mariah; Goodwin, Rachel P.; Goodwin, Elliot; Musa, Ameer; Mathbout, Mohammad; Ogunbayo, Gbolahan; Kim, Sun Moon; Abdel‐Latif, Ahmed; Ziada, Khaled M.

doi:10.1016/j.amjcard.2018.04.010

Cited by 7 publications

(6 citation statements)

References 24 publications

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“…Furthermore, in most cases, more than two NC-balloons (66%, n = 221) and domestic stents (63.8%, n = 221) were used. The implementation of plaque modification of tortuous and calcified lesions ( 23 – 26 ) and the optimization of stent implantation ( 27 , 28 ) might have contributed significantly to the relatively good short-term prognosis in this study. Of course, it is also dependent on the interventional cardiologist’s experience and operation skills ( 22 ).…”

Section: Discussionmentioning

confidence: 88%

Guidezilla™ guide extension catheter I for transradial coronary intervention

Lei

Liang

Fang

et al. 2022

Front. Cardiovasc. Med.

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BackgroundPercutaneous coronary intervention (PCI) is the preferred treatment method for coronary artery diseases (CAD). This study aimed to evaluate the effectiveness and complications of the Guidezilla™ guide extension catheter I (GGEC I) in transradial coronary intervention (TRI).MethodsThis case series study included patients with CAD who underwent TRI using the GGEC I between August 2016 and January 2019 at the First Affiliated Hospital of Xi’an Jiaotong University.ResultsA total of 221 patients aged 65.1 ± 9.26 years were included. Coronary angiography results indicated that most patients (77.8%) had triple-vessel lesions, including 47.5% with chronic total occlusion (CTO). A total of 237 target lesions were treated, most being type C lesions (95.8%). The most common indication for GGEC I use was heavy calcification (67%), followed by extreme tortuosity (12.2%), extreme tortuosity and heavy calcification (10.9%), distally located lesion (4.5%), picking up the retrograde wire (3.2%), anomalous vessel origin (1.8%), and releasing the burr incarceration (0.4%). The mean operation time was 58 min, and the overall success rate was 94.1%. Four patients received a drug-coated balloon. No significant differences were found in operation time and success rate among the low (<23), intermediate (23–32), and severe (>32) CAD groups based on SYNTAX score stratification (P > 0.05). Two subacute thrombosis cases each were reported perioperatively, during hospitalization, and at the 1-month follow-up.ConclusionThe GGEC I might have advantages for TRI and is unaffected by SYNTAX score stratification.

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Section: Discussionmentioning

confidence: 88%

Guidezilla™ guide extension catheter I for transradial coronary intervention

Lei

Liang

Fang

et al. 2022

Front. Cardiovasc. Med.

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“…Misumida et al (27) detected that SYNTAX score 2 was correlated with mortality. However, some predictors such as diabetes mellitus (28), heart failure (29), chronic renal failure (30) and so on, which proved related to MACCE in other studies, were not included in our finding.…”

Section: Discussionmentioning

confidence: 99%

Second drug-eluting stent implantation versus coronary artery bypass grafting in treatment of young patients with left main and/or multivessel coronary disease

Chen

Zhang

Yan

et al. 2019

Preprint

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Background Many studies have compared outcomes of coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) for complex coronary artery disease (CAD). However, no trials have focused on young patients (< 45 years) with complex CAD. We conducted a retrospective evaluation to compare the outcomes of a 2nd drug-eluting stent and CABG in young patients with LM or three-vessel disease. Methods In the young patients with complex CAD who underwent PCI or CABG, Kaplan-Meier analysis and Cox regression before and after propensity-score matching were used to compare major adverse cardiac and cerebrovascular events (MACCE), including myocardial infarction (MI), stoke, death and repeat revascularization. Results During the follow-up, MACCE occurred in 20.5% of patients in the PCI group and 8.6% in the CABG group (hazard ratio [HR]: 3.263, 95% confidence interval [CI]: 1.379 to 7.722, p=0.007). Repeat revascularization occurred more frequently in the PCI group (18.9% vs. 3.7% respectively, HR: 6.968, 95% CI: 2.036 to 23.842, p=0.002). There were no significant differences in other endpoints. After propensity-score matching, no conclusions were changed. Conclusions In young patients with LM or three-vessel disease, PCI showed a higher incidence of MACCE, which was mainly driven by repeat revascularization. However that did not translate into hard endpoints differences. Therefore, PCI is an alternative treatment to CABG in young patients with complex CAD.

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“…Kosmoidou et al [21] found that an elevated baseline CRP level was strongly associated with subsequent death, MI and stroke. Misumida et al [22] determined that the SYNTAX score 2 was correlated with mortality. However, some predictors such as diabetes mellitus [23], heart failure [24], chronic renal failure [25], and so on, which have been proven to be related to MACCE in other studies, were not included in our study.…”

Section: Discussionmentioning

confidence: 99%

Second Generation Drug-Eluting Stent Implantation versus Coronary Artery Bypass Grafting in the Treatment of Young Patients with Left Main and/or Multivessel Coronary Disease

Chen

Zhang

Yan

et al. 2020

Journal of Interventional Cardiology

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Background. Many studies have compared the outcomes of coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) for complex coronary artery disease (CAD). However, no trials have focused on young patients (<45 years) with complex CAD. We conducted a retrospective evaluation to compare the outcomes of a second-generation drug-eluting stent (DES) and CABG in young patients with LM or three-vessel disease. Methods. In young patients with complex CAD who underwent PCI or CABG, a Kaplan-Meier analysis and Cox regression before and after propensity score matching were used to compare major adverse cardiac and cerebrovascular events (MACCE), including myocardial infarction (MI), stroke, death, and repeat revascularization. Results. During follow-up, MACCE occurred in 20.5% of patients in the PCI group and 8.6% of patients in the CABG group (hazard ratio (HR): 3.263, 95% confidence interval (CI): 1.379 to 7.722, p=0.007). Repeat revascularization occurred more frequently in the PCI group (18.9% vs. 3.7%, respectively, HR: 6.968, 95% CI: 2.036 to 23.842, p=0.002). There were no significant differences in the other endpoints. After propensity score matching, no conclusions were modified. Conclusions. In young patients with LM or three-vessel disease, PCI showed a higher incidence of MACCE, which was mainly driven by repeat revascularization. However, this did not translate into hard endpoint differences. Therefore, PCI is an alternative treatment to CABG in young patients with complex CAD.

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Prognostic Value of Anatomical SYNTAX Score and SYNTAX Score II in Veterans With Left Main and/or Three-Vessel Coronary Artery Disease

Cited by 7 publications

References 24 publications

Guidezilla™ guide extension catheter I for transradial coronary intervention

Guidezilla™ guide extension catheter I for transradial coronary intervention

Second drug-eluting stent implantation versus coronary artery bypass grafting in treatment of young patients with left main and/or multivessel coronary disease

Second Generation Drug-Eluting Stent Implantation versus Coronary Artery Bypass Grafting in the Treatment of Young Patients with Left Main and/or Multivessel Coronary Disease

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