Prognostic value of admission serum glucose-phosphate ratio in predicting the 6-month outcome of patients with severe traumatic brain injury: A retrospective study

Qiu, Shen-Zhong; Zheng, Guan-Rong; Chen, Bin; Jian, Huang; Shen, Jia; Mao, Wei

doi:10.1016/j.cca.2020.08.038

Cited by 6 publications

(4 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 26 Similarly, serum glucose-phosphate ratio was found to correlate with severity and 6-month mortality in patients with severe traumatic brain injury. 27 Conversely, You and colleagues 18 reported no significant association between serum phosphate and excellent outcomes among patients with acute ICH. The diverse correlation between serum phosphate and prognosis of patients with ICH may be attributed to the different subjects’ characteristics and study designs.…”

Section: Discussionmentioning

confidence: 99%

Association Between Admission Serum Phosphate Level and All-Cause Mortality Among Patients with Spontaneous Intracerebral Hemorrhage

Hong¹,

Wang²,

Xiong³

et al. 2021

RMHP

View full text Add to dashboard Cite

Background: Hypophosphatemia was reported to frequently occur in patients with nontraumatic intracranial hemorrhage (ICH); however, the correlation between hypophosphatemia and outcomes of ICH remains unclear. This study aimed to examine the association between admission serum phosphate and all-cause mortality among patients with mildmoderate spontaneous ICH (sICH). Methods: A total of 851 patients with sICH were enrolled. Serum phosphate was acquired within 24 hours on admission, and participants were divided according to phosphate quartiles. The primary outcome was all-cause mortality within 90 days, and univariate and multivariate models were employed to estimate the mortality risk. Results: There were significant differences among sICH patients with different phosphate quartiles in terms of age, diastolic blood pressure (DBP), activated partial thromboplastin time (APTT), platelet count, and incidence of respiratory failure events on admission (P < 0.05). Log rank test showed a significant difference in the mortality risk among sICH patients with each phosphate quartile. Univariate Cox regression analysis revealed that age, smoking, DBP, APTT, NIH stroke scale (NIHSS) score, hematoma volume and serum phosphate might be associated with the 90-day all-cause mortality in patients with sICH (P < 0.05). Multivariable Cox regression analysis showed that the crude mortality was 4.3-fold greater in sICH patients with serum phosphate Q1 than those with Q4 (P < 0.001), and remained 3.18-fold higher after adjusting for age, smoking, DBP, APTT, NIHSS score, hematoma volume and early withdrawal of life-sustaining therapy (P = 0.011). Representative operating curve (ROC) analysis showed that admission serum phosphate was predictable for all-cause mortality within 90 days in patients with sICH (area under the ROC = 0.628, P < 0.001). Conclusion:Low admission serum phosphate is strongly associated with a high risk of mortality in patients with mild-moderate sICH, and hypophosphatemia may be a prognostic marker for all-cause mortality in patients with mild-moderate sICH.

show abstract

Section: Discussionmentioning

confidence: 99%

Association Between Admission Serum Phosphate Level and All-Cause Mortality Among Patients with Spontaneous Intracerebral Hemorrhage

Hong¹,

Wang²,

Xiong³

et al. 2021

RMHP

View full text Add to dashboard Cite

show abstract

“…The cognitive rehabilitation intervention with the participation of patients' family members and therapists organically combines the mental and behavior patterns of patients. Through repeated training, patients can synthesize, and analyze information, so as to enhance their quality of life [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…rough repeated training, patients can synthesize, and analyze information, so as to enhance their quality of life [27].…”

Section: Discussionmentioning

confidence: 99%

Effect of Early Rehabilitation Nursing on Motor Function and Living Ability of Patients with Traumatic Brain Injury Based on Orem’s Self-Care Theory

Yang

Niu

2022

Computational Intelligence and Neuroscience

View full text Add to dashboard Cite

Objective. To explore the effect of early rehabilitation nursing on motor function and living ability of patients with traumatic brain injury (TBI) based on Orem’s self-care theory. Methods. A total of 60 patients with TBI treated in our hospital from February 2019 to June 2021 were enrolled. The patients were randomly divided into a control group and a research group. The control group adopted the early rehabilitation nursing model, while the research group adopted the early rehabilitation nursing model based on Orem’s self-nursing theory. Nursing satisfaction, Fugl-Meyer score, NIH-SS score, Barthel index, quality of life score, and compliance were in the comparison of the two groups. Results. The nursing satisfaction of the research group was higher than that of the control group ( P < 0.05). Compared with the control group, the Fugl-Meyer scores of the research group were higher at 1 month, 2 months, and 3 months after nursing ( P < 0.05). After nursing, the NIH-SS score of the two groups decreased. In the comparison of the two groups, the NIH-SS score of the research group at 1 month, 2 months, and 3 months after nursing was lower ( P < 0.05). After nursing, the Barthel index of the two groups increased. In the comparison of the two groups, the Barthel index of the research group was higher compared to the control group at 1 month, 2 months, and 3 months after nursing ( P < 0.05). The scores of physiological function, psychological function, social function, and health self-cognition in the research group were lower ( P < 0.05). The compliance rate of the research group was higher than that of the control group ( P < 0.05). Conclusion. Patients with TBI receive early rehabilitation nursing based on Orem’s self-care theory, which can effectively improve patient satisfaction and compliance and achieve the purpose of improving motor function and living ability. This nursing program is worth popularizing in the clinic.

show abstract

“…However, the AUC was 0.772, indicating only a modest prognostic value for neurological outcomes. In a retrospective study of patients with traumatic brain injury [19], as each quartile of serum glucose-phosphate ratio levels increased, the Glasgow Coma Scale score, overall probability, and mortality worsened, with an AUC of approximately 0.885 in all categories. In a study by Jung et al [8], the ROC curve showed an AUC of 0.805 for SP levels, poor neurological outcomes, and hospital discharge.…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of serum phosphate level in elderly post-cardiac arrest patients

2022

View full text Add to dashboard Cite

Prognosticating the neurological outcomes of cardiac arrest is important. A recent study has shown that serum phosphate (SP) may be a prognostic indicator for poor neurological outcomes in cardiac arrest patients. Due to advancements in medicine, more elderly patients survive cardiac arrest than ever before, and prognostication of the markers in this population has not been studied previously. We aimed to confirm the hypothesis that a higher SP level predicts a poor neurological outcome of cardiac arrest, even in elderly patients. This retrospective observational study included post-cardiac arrest elderly patients (aged ≥ 65 years) who were admitted to three hospitals in urban areas in South Korea from December 2013 to February 2020. Data regarding patient characteristics, laboratory values, and neurological outcomes at 28 days were collected from patients’ medical records. The primary outcome was poor neurological outcome (Cerebral Performance Category scores 3–5) at 28 days. Of the 389 eligible patients, 334/389 had poor neurological outcomes at 28 days. SP levels were significantly higher in those with poor neurological outcomes than in those with good neurological outcomes (7.32 vs. 5.01, p < 0.001). Multivariate logistic regression analysis also showed that SP levels were independently associated with neurological outcomes. Receiver operating characteristic curve analysis of SP levels showed an area under the curve of 0.772. Higher SP levels are associated with poor neurological outcomes after cardiac arrest in the elderly population.

show abstract

Prognostic value of admission serum glucose-phosphate ratio in predicting the 6-month outcome of patients with severe traumatic brain injury: A retrospective study

Cited by 6 publications

References 20 publications

Association Between Admission Serum Phosphate Level and All-Cause Mortality Among Patients with Spontaneous Intracerebral Hemorrhage

Association Between Admission Serum Phosphate Level and All-Cause Mortality Among Patients with Spontaneous Intracerebral Hemorrhage

Effect of Early Rehabilitation Nursing on Motor Function and Living Ability of Patients with Traumatic Brain Injury Based on Orem’s Self-Care Theory

Prognostic value of serum phosphate level in elderly post-cardiac arrest patients

Contact Info

Product

Resources

About