Prognostic value of admission red blood cell distribution width in acute pancreatitis: a systematic review

Goyal, Hemant; Awad, Hamza H.; Hu, Zhide

doi:10.21037/atm.2017.06.61

Cited by 48 publications

(50 citation statements)

References 41 publications

(53 reference statements)

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“…The red cell distribution width (RDW) is a quantitative measure of variability in the size of circulating erythrocytes with higher values reflecting greater heterogeneity in cellular sizes. As a part of complete blood cell count, RDW is generally determined among hospitalized patients because of its simplicity and availability [10,11]. RDW is typically used to differentiate the different causes of anemia [12], however, the present studies have observed that RDW could be used as a predictive marker in various diseases, including cardiovascular disease [11,13], malignant tumors [14,15], acute pancreatitis [16].…”

Section: Introductionmentioning

confidence: 71%

Prognostic value of Red Blood Cell Distribution Width in Acute Kidney Injury Patients: A Systematic Review and Meta-analysis

Liu

Wang

Yao

et al. 2019

Preprint

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Background:The conflicting result with regard to Red Cell Distribution Width (RDW) with Acute Kidney Injury (AKI) has been reported. This systematic review and meta-analysis were aimed to investigate RDW and prognostic value in AKI patients. Methods/Main Results:This meta-analysis included 1251 cases and 1663 controls with a total of 7 enrolled published papers. The results of RDW levels were significantly associated with patients of AKI (WMD=1.127, 95% CI=0.426-1.827; P=0.002), with statistically significant heterogeneity (I 2 =95.80%, P heterogeneity =0.000, random-effects model). 2 Conclusions:In conclusion, the results of this present meta-analysis suggest that the RDW value is a positive prognostic indicator in patients with AKI. However, these results were obtained on the basis of RCS or small sample sizes studies.Further functional studies with additional data would be needed to validate our findings.

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Section: Introductionmentioning

confidence: 71%

Prognostic value of Red Blood Cell Distribution Width in Acute Kidney Injury Patients: A Systematic Review and Meta-analysis

Liu

Wang

Yao

et al. 2019

Preprint

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“…Red blood distribution width (RDW) is a routine parameter of the complete blood count test, which is easily obtained and inexpensive [166,167]. It is commonly performed in the assessment of almost all patients at the time of admission.…”

Section: Red Blood Cell Distribution Widthmentioning

confidence: 99%

Multifactorial Scores and Biomarkers of Prognosis of Acute Pancreatitis: Applications to Research and Practice

Silva-Vaz

Abrantes

Castelo‐Branco

et al. 2020

IJMS

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Acute pancreatitis (AP) is a severe inflammation of the pancreas presented with sudden onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by severe local and systemic complications. Numerous studies have been published about the pathogenesis of AP; however, the precise mechanism behind this pathology remains unclear. Extensive research conducted over the last decades has demonstrated that the first 24 h after symptom onset are critical for the identification of patients who are at risk of developing complications or death. The identification of these subgroups of patients is crucial in order to start an aggressive approach to prevent mortality. In this sense and to avoid unnecessary overtreatment, thereby reducing the financial implications, the proper identification of mild disease is also important and necessary. A large number of multifactorial scoring systems and biochemical markers are described to predict the severity. Despite recent progress in understanding the pathophysiology of AP, more research is needed to enable a faster and more accurate prediction of severe AP. This review provides an overview of the available multifactorial scoring systems and biochemical markers for predicting severe AP with a special focus on their advantages and limitations.

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“…Red blood cell distribution width (RDW) represents the variability of form and size in red blood cells of a subject and is a hemogram index that is used for the differential diagnosis of anemia [1]. High RDW has been associated with increased mortality in patients with coronary disease [2], cardiac arrest [3], heart failure [4], pancreatitis [5], liver disease [6], sepsis [7,8], or traumatic brain injury [9].…”

Section: Introductionmentioning

confidence: 99%

Early Mortality of Brain Infarction Patients and Red Blood Cell Distribution Width

et al. 2020

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Background: Meta-analysis has found that high baseline red blood cell distribution width (RDW) is associated with increased long-term mortality (mortality at one year or more) in ischemic stroke. The objectives of this study were to determine whether there is an association between RDW and 30-day mortality, and to explore whether RDW during the first week of ischemic stroke could be a 30-day mortality biomarker. Methods: We included patients with malignant middle cerebral artery infarction (MMCAI). RDW at days 1, 4, and 8 of MMCAI were determined. The end-point study was 30-day mortality. Results: We found that survivor (n = 37) in respect to non-survivor patients (n = 37) had lower RDW at days 1 (p < 0.001), 4 (p < 0.001), and 8 (p = 0.02). The area under curve (95% CI) for prediction of 30-day mortality by RDW at days 1, 4, and 8 of MMCAI were 0.80 (0.69–0.89; p < 0.001), 0.79 (0.66–0.89; p < 0.001), and 0.73 (0.58–0.84; p = 0.02). Regression analysis showed an association between RDW (odds ratio = 1.695; 95% CI = 1.230–2.335; p < 0.001) and 30-day mortality. Conclusions: The association between RDW and early mortality, and the potential role of RDW during the first week of MMCAI as a prognostic biomarker of early mortality were the main novelties of our study.

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Prognostic value of admission red blood cell distribution width in acute pancreatitis: a systematic review

Cited by 48 publications

References 41 publications

Prognostic value of Red Blood Cell Distribution Width in Acute Kidney Injury Patients: A Systematic Review and Meta-analysis

Prognostic value of Red Blood Cell Distribution Width in Acute Kidney Injury Patients: A Systematic Review and Meta-analysis

Multifactorial Scores and Biomarkers of Prognosis of Acute Pancreatitis: Applications to Research and Practice

Early Mortality of Brain Infarction Patients and Red Blood Cell Distribution Width

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