Prognostic value of 18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in infective endocarditis

San, Sovannarith; Ravis, Eléonore; Tessonier, Laetitia; Philip, Mary; Oliver, L; Arregle, Florent; Martel, Hélène; Renard, S.; Gouriet, Frédérique; Casalta, Jean‐Paul; Collart, Frédéric; Drancourt, Michel; Raoult, Didier; Habib, Gilbert

doi:10.1016/j.acvdsp.2019.09.115

Cited by 2 publications

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“…Recently, 18 F‐FDG PET has presented potential value in providing predictive information about the risk of complications associated with infections. In a study including patients with prosthetic valve endocarditis and those with native valve endocarditis, the presence of a high level of local inflammation as assessed by 18 F‐FDG PET/CT was independently associated with a high risk of new‐onset EE 23 …”

Section: Predictors For Eementioning

confidence: 99%

Infective endocarditis complicated by embolic events: Pathogenesis and predictors

Wang

2021

Clinical Cardiology

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Background Infective endocarditis (IE) continues to be associated with great challenges. Embolic events (EE) are frequent and life‐threatening complications in IE patients. It remains challenging to predict and assess the embolic risk in individual patients with IE accurately. Hypothesis Accurate prediction of embolization is critical in the early identification and treatment of risky and potentially embolic lesions in patients with IE. Methods We searched the PubMed, Web of Science, and Google Scholar databases using a range of related search terms, and reviewed the literatures about the pathogenesis and embolic predictors of IE. Results The development of IE and its complications is widely accepted as the result of complex interactions between microorganisms, valve endothelium, and host immune responses. The predictive value of echocardiographic characteristics is the most powerful for EE. In addition, both easily obtained blood biomarkers such as C‐reactive protein, mean platelet volume, neutrophil‐to‐lymphocyte ratio, anti‐β2‐glycoprotein I antibodies, D‐Dimer, troponin I, matrix metalloproteinases, and several microbiological or clinical characteristics might be promising as potential predictors of EE. Conclusion Our review provides a synthesis of current knowledge regarding the pathogenesis and predictors of embolism in IE along with a review of potentially emerging biomarkers.

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Section: Predictors For Eementioning

confidence: 99%

Infective endocarditis complicated by embolic events: Pathogenesis and predictors

Wang

2021

Clinical Cardiology

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“…Very recent data proved the prognostic value of ( 18 F)FDG PET/CT in PVE. In a large retrospective study on 173 patients with left-sided IE and examined after seven days from the first antibiotic administration, a moderate to intense valvular ( 18 F)FDG uptake was predictive of major adverse cardiac events defined as in-hospital death, one-year death, recurrence of IE, acute cardiac insufficiency, symptomatic embolism under antibiotics, and nonscheduled rehospitalization for cardiovascular indication [ 54 ]. These results reinforce the utility of ( 18 F)FDG PET/CT in PVE and justify its use in this population, not only for diagnostic purposes, but also for prognostic assessment.…”

Section: Early and Late Prosthetic Valve Infective Endocarditis (Pmentioning

confidence: 99%

Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection

Galea

Bandera

Lauri

et al. 2020

JCM

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Infective endocarditis (IE) is a serious cardiac condition, which includes a wide range of clinical presentations, with varying degrees of severity. The diagnosis is multifactorial and a proper characterization of disease requires the identification of the primary site of infection (usually the cardiac valve) and the search of secondary systemic complications. Early depiction of local complications or distant embolization has a great impact on patient management and prognosis, as it may induce to aggressive antibiotic treatment or, in more advanced cases, cardiac surgery. In this setting, the multimodality imaging has assumed a pivotal role in the clinical decision making and it requires the physician to be aware of the advantages and disadvantages of each imaging technique. Echocardiography is the first imaging test, but it has several limitations. Therefore, the integration with other imaging modalities (computed tomography, magnetic resonance imaging, nuclear imaging) becomes often necessary. Different strategies should be applied depending on whether the infection is suspected or already ascertained, whether located in native or prosthetic valves, in the left or right chambers, or if it involves an implanted cardiac device. In addition, detection of extracardiac IE-related lesions is crucial for a correct management and treatment. The aim of this review is to illustrate strengths and weaknesses of the various methods in the most common clinical scenarios.

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Prognostic value of 18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in infective endocarditis

Cited by 2 publications

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Infective endocarditis complicated by embolic events: Pathogenesis and predictors

Infective endocarditis complicated by embolic events: Pathogenesis and predictors

Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection

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