Prognostic value and immune regulatory role of dynamin 1-like in lung adenocarcinoma
Wenping Song,
Xuan Wu,
Shuai Wang
et al.
Abstract:Background
Lung adenocarcinoma (LUAD) is the most common histological subtype of non-small cell lung cancer (NSCLC), with poor treatment outcomes worldwide. Dynamin-related protein 1 (DRP1), which is encoded by the dynamin 1-like (
DNM1L
) gene, acts as a regulator of mitochondrial fission and plays crucial roles in tumor initiation and progression. However, the clinical value and immune regulation of
DNM1L
in LUAD have not been explored.
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