Prognostic significance of parapharyngeal space venous plexus and marrow involvement: Potential landmarks of dissemination for stage I-III nasopharyngeal carcinoma

Diagnostic, Therapeutic and Evolutionary Characteristics of Nasopharyngeal Cancer in Morocco

“…Cheng et al [28] found parapharyngeal space extension to be the key factor in distant metastasis even in N1 and N2 NPC. However, Teo et al [29] did not find parapharyngeal space involvement to be an independent significant prognostic factor in a study of 903 patients.…”

Chemoradiotherapy regimens for locoregionally advanced nasopharyngeal carcinoma: A Bayesian network meta-analysis

“…Regardless of the reason, there is mounting evidence that CRT alone is a viable option for the treatment of advanced NPC. However, it remains to be seen whether adjuvant therapy would be more appropriate for certain patient subgroups, as suggested by results from other studies [47]. Additional information is anticipated from a recently completed multicentre randomised trial (NCT00677118) comparing CRT-A and CRT.…”

Treatment Outcomes After Radiotherapy Alone for Patients With Early-Stage Nasopharyngeal Carcinoma

“…Published data have shown that invasion of the parapharyngeal space will decrease the local control rate and increase the possibility of distant metastasis (18)(19)(20). Cheng et al (21) collected data from 364 NPC patients with Stage I-III disease according to the International Union Against Cancer (2002) staging system. All the patients were divided into two groups according to invasion of the parapharyngeal space and skull bone marrow involvement: a low-risk group (T1-T2aN0-N2) and an intermediate-risk group (T2b-T3N0-N2).…”