Prognostic Significance of Left Ventricular Diastolic Dysfunction Assessed by Color M-mode Doppler Echocardiography in Patients With Chronic Left Ventricular Systolic Dysfunction
Abstract:Background. Color M-mode Doppler echocardiography provides accurate evaluation of LV diastolic function noninvasively and is reportedly preload independent compared with pulsed Doppler transmitral velocity indexes. This study aimed to determine the prognostic significance of left ventricular (LV) diastolic function in patients with different degrees of chronic LV systolic dysfunction using color M-mode Doppler echocardiography.
Methods.A total of 98 consecutive subjects (mean age 57 years, 78 males) with LV sy… Show more
“…Therefore, the results are consistent with the hypothesis of this study. Relation to previous studies Systolic and diastolic LV dysfunction is the basic cause of congestive heart failure [15][16][17]. However, associated mitral valve dysfunction is also critically important in patients with congestive heart failure [18][19][20].…”
IntroductionSerious hemodynamic deterioration by left ventricular outflow tract (LVOT) obstruction following catecholamine infusion in anteroseptal acute myocardial infarction (AMI) has been reported [1][2][3][4][5]. It has been reported that LVOT obstruction in hypertrophic obstructive cardiomyopathy (HOCM) is related to 1) excessive anterior mitral leaflets beyond coaptation due to anteriorly located papillary muscles and abnormally elongated leaflets [6][7][8][9][10][11][12], 2) excessive posterior mitral leaflets [13], 3) reduced chordal tension, and others. However, the mechanism of LVOT obstruction following catecholamine infusion in anteroseptal AMI without left ventricular hypertrophy (LVH) has not been established.In anteroseptal AMI following catecholamine infusion without LVH, reduced mitral annular size due to hyperkinetic basal posterior wall can potentially cause excessive mitral leaflets, leading to its systolic anterior motion (SAM) and LVOT obstruction (Fig. 1). Therefore, the purpose of this study is to investigate the relation between the decrease in mitral annular dimension and the LVOT obstruction following catecholamine infusion in a canine model of AMI.
Left Ventricular Outflow Tract Obstruction
“…Therefore, the results are consistent with the hypothesis of this study. Relation to previous studies Systolic and diastolic LV dysfunction is the basic cause of congestive heart failure [15][16][17]. However, associated mitral valve dysfunction is also critically important in patients with congestive heart failure [18][19][20].…”
IntroductionSerious hemodynamic deterioration by left ventricular outflow tract (LVOT) obstruction following catecholamine infusion in anteroseptal acute myocardial infarction (AMI) has been reported [1][2][3][4][5]. It has been reported that LVOT obstruction in hypertrophic obstructive cardiomyopathy (HOCM) is related to 1) excessive anterior mitral leaflets beyond coaptation due to anteriorly located papillary muscles and abnormally elongated leaflets [6][7][8][9][10][11][12], 2) excessive posterior mitral leaflets [13], 3) reduced chordal tension, and others. However, the mechanism of LVOT obstruction following catecholamine infusion in anteroseptal AMI without left ventricular hypertrophy (LVH) has not been established.In anteroseptal AMI following catecholamine infusion without LVH, reduced mitral annular size due to hyperkinetic basal posterior wall can potentially cause excessive mitral leaflets, leading to its systolic anterior motion (SAM) and LVOT obstruction (Fig. 1). Therefore, the purpose of this study is to investigate the relation between the decrease in mitral annular dimension and the LVOT obstruction following catecholamine infusion in a canine model of AMI.
Left Ventricular Outflow Tract Obstruction
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