Prognostic Significance of
Incidental Renal Cell Carcinoma

Bretheau, D; Lechevallier, É.; Eghazarian, C.; Grisoni, Vincent; Coulange, C.

doi:10.1159/000475189

Cited by 121 publications

(53 citation statements)

References 10 publications

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“…The dominant cell type was clear cells in 59% (68), chromophile cells in 23% (26), chromophobe in 10%, and sarcomatous in 8%.…”

Section: Resultsmentioning

confidence: 99%

“…[24][25][26][27][28] In this study, 78% of the diagnoses were made by ultrasound and 20% by CT scan. These data show that the ultrasonography examination has an important role in the early detection of such tumors, considering that it is used for evaluating cardiac, hepatic, gallbladder, pancreas and gynecological diseases as well as in routine health check-ups.…”

Section: Discussionmentioning

confidence: 99%

“…In the present study, tumor location was equally distributed between the two kidneys, but some series have shown greater numbers of incidental cases in the right kidney. 24,26,27 Currently, large centers defend the use of some type of screening. 9 The screening of high risk populations, especially for those undergoing dialysis or with von Hippel-Lindau disease, and for those over 50 years of age, is advised.…”

Section: Discussionmentioning

confidence: 99%

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Incidental and symptomatic renal tumors: impact on patient survival

et al. 2002

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CONTEXT: Renal cell carcinoma is the third most frequent genitourinary neoplasia, and there is currently an increase in the incidental diagnosis of tumors confined to the kidneys. OBJECTIVE: To study the survival of patients with incidental and symptomatic renal tumors who have undergone nephrectomy.DESIGN: Retrospective. SETTING: Hospital Sírio Libanês and Beneficência Portuguesa de São Paulo. PARTICIPANTS: 115 patients with diagnosis of renal cell carcinoma, operated on by the same group of surgeons and evaluated by a single pathologist. MAIN MEASUREMENTS: Sex, age and diagnosis method, analyzed in two groups, according to the tumor diagnosis: Group 1 with incidental diagnosis and Group 2 with symptomatic tumors. The anatomopathological characteristics and patient survival in both groups were evaluated. A statistical analysis was performed using the Student t, chi-squared, log rank and Kaplan-Meyer tests. RESULTS: Among the studied patients, 59(51%) had an incidental diagnosis, with 78% diagnosed by ultrasonography, 20% by computerized tomography scan and 2% during surgeries; 56 patients (49%) were symptomatic. Tumor locations were equally distributed between the two kidneys, and the surgery was conservative for 24% of the incidental and 9% of the symptomatic group. In the incidental group only one patient had tumor progression and there was no death, while in the symptomatic group there were 5 progressions and 10 deaths. The 5-year specific cancer-free survival was 100% in the incidental and 80% in the symptomatic group (p = 0.001) while the disease-free rate was 98% in the incidental and 62% in the symptomatic group (p < 0001). CONCLUSION: Incidental renal tumor diagnosis offers better prognosis, providing longer disease-free survival.

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“…The dominant cell type was clear cells in 59% (68), chromophile cells in 23% (26), chromophobe in 10%, and sarcomatous in 8%.…”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Incidental and symptomatic renal tumors: impact on patient survival

et al. 2002

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“…It is generally postulated that the increased incidence rates reflect earlier diagnosis at an earlier stage, largely due to more liberal use and better quality of modern radiological imaging techniques such as ultrasonography, computerized tomography (CT) and magnetic resonance imaging (MRI) [4,[7][8][9][10]. An interesting observation is that a higher proportion of women and elderly are noted within the incidentally detected cohorts [4,[11][12][13].…”

Section: Incidencementioning

confidence: 99%

“…Some studies have shown a survival advantage in patients with early or incidental diagnosed RCC. These investigators have demonstrated that RCC is localized in more than 85% in incidentally discovered tumors, compared to 40-45% in symptomatic cases [8,[48][49][50][51][52].…”

Section: Screeningmentioning

confidence: 99%