Prognostic Significance of Incident Complete Left Bundle Branch Block Observed Over a 40-Year Period

Imanishi, Ryo; Seto, Shinji; Ichimaru, Shinichiro; Nakashima, Eiji; Yano, Katsusuke; Akahoshi, Masazumi

doi:10.1016/j.amjcard.2006.03.044

Cited by 94 publications

(53 citation statements)

References 18 publications

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“…A statistically significant difference in the frequency of LBBB between men and women was only present in the age group from 60 to 79.9 years, which is understandable, given the usually late onset of LBBB. 26 In this group, the prevalence was 2.9% in men and 3.3% in women. Other studies have also found similar prevalences of LBBB in both sexes 3,26 but none of them further explored the slightly higher prevalence of LBBB among women.…”

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confidence: 99%

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Prevalence of electrocardiographic abnormalities in primary care patients according to sex and age group. A retrospective observational study

et al. 2018

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BACKGROUND: Knowledge of the prevalence of electrocardiographic abnormalities in a population is useful for interpreting the findings. The aim here was to assess the prevalence of electrocardiographic abnormalities and self-reported comorbidities and cardiovascular risk factors according to sex and age group among Brazilian primary care patients. DESIGN AND SETTING: Observational retrospective study on consecutive primary care patients in 658 cities in the state of Minas Gerais, Brazil, whose digital electrocardiograms (ECGs) were sent for analysis to the team of the Telehealth Network of Minas Gerais (TNMG). METHODS: All ECGs analyzed by the TNMG team in 2011 were included. Clinical data were self-reported and electrocardiographic abnormalities were stratified according to sex and age group. RESULTS: A total of 264,324 patients underwent ECG examinations. Comorbidities and cardiovascular risk factors were more frequent among women, except for smoking. Atrial fibrillation and flutter, premature beats, intraventricular blocks, complete right bundle branch block and left ventricular hypertrophy were more frequent among men, and nonspecific ventricular repolarization abnormalities and complete left bundle branch block among women. CONCLUSION: Electrocardiographic abnormalities were relatively common findings, even in the younger age groups. The prevalence of electrocardiographic abnormalities increased with age and was higher among men in all age groups, although women had higher frequency of self-reported comorbidities.

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confidence: 99%

“…26 In this group, the prevalence was 2.9% in men and 3.3% in women. Other studies have also found similar prevalences of LBBB in both sexes 3,26 but none of them further explored the slightly higher prevalence of LBBB among women.…”

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confidence: 99%

Prevalence of electrocardiographic abnormalities in primary care patients according to sex and age group. A retrospective observational study

et al. 2018

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“…First, the prognosis of MPS in patients with LBBB or RVA pacing was assessed in patients with a higher mean age compared with studies that assessed the prognostic value of MPS in patients with normal left ventricular conduction. Also, patients with LBBB are known to have a higher cardiac event rate than patients with right bundle branch block or normal left ventricular activation patterns [33][34][35]. For RVA pacing this is less well known.…”

Section: The Prognostic Value Of Mpsmentioning

confidence: 99%

Patients with left bundle branch block pattern and high cardiac risk myocardial SPECT: does the current management suffice?

et al. 2011

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Introduction Myocardial perfusion SPECT (MPS) is frequently used for cardiovascular risk stratification. The significance of MPS in patients with abnormal electrical ventricular activation is often questionable. This review assesses the value of MPS for risk stratification of patients with intrinsic left bundle branch block or that due to right ventricular apical pacing. Methods We reviewed the literature by a search of the MEDLINE database (January 1980 to September 2010). The terms prognosis or prognostic value were combined with SPECT and LBBB or pacing or pacemakers. MPS was categorised as low and high risk according to the original definitions. Results We identified 11 studies suitable for review. A lowrisk MPS is associated with a low risk of cardiac events whereas high-risk MPS carries a 4.8-fold increased risk, 95% CI [3.2 -7.2] (p < 0.0001). Despite secondary prevention and an improved medical and interventional care, these figures have hardly changed over time. Conclusion and clinical implications A low-risk MPS permits a policy of watchful waiting whereas a high-risk MPS requires further analysis and treatment. The persistent high cardiac death and acute myocardial infarction rate after a high-risk MPS suggest that the current management of these patients does not suffice and needs reconsideration.

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“…Also, the left and the right bundle branch block. This leads to a delayed activation of the ventricles [12,18,20,27]. The arrhythmia may also be generated by Ionic effects within the rapid conduction system [7].…”

Section: Introductionmentioning

confidence: 99%

Stability Analysis of Decoupled Time-stepping Schemes for the Specialized Conduction System/myocardium Coupled Problem in Cardiology

Aouadi

Mbarki

Zemzemi

2017

Math. Model. Nat. Phenom.

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Abstract. The Purkinje network is the rapid conduction system in the heart. It ensures the physiological spread of the electrical wave in the ventricles. In this work, we consider a problem that models the coupling between the Purkinje network and the myocardium. We first prove the stability of the space semi-discretized problem. Then we present four different strategies for solving the Purkinje/ myocardium coupling. The strategies are based on different time discretization of the coupling terms. The first scheme is fully coupled, where the coupling terms are considered implicit. The second and the third schemes are based on Gauss-Seidel time-splitting schemes where one coupling term is considered explicit and the other is implicit. The last is a Jacobi-like time-splitting scheme where both coupling terms are considered explicit. Our main result is the proof of the stability of the three considered schemes under the same restriction on the time step. Moreover, we show that the energy of the problem is slightly affected by the time-splitting schemes. We illustrate the theoretical result by different numerical simulations in 2D. We also conduct 3D simulations using physiologically detailed ionic models.

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Prognostic Significance of Incident Complete Left Bundle Branch Block Observed Over a 40-Year Period

Cited by 94 publications

References 18 publications

Prevalence of electrocardiographic abnormalities in primary care patients according to sex and age group. A retrospective observational study

Prevalence of electrocardiographic abnormalities in primary care patients according to sex and age group. A retrospective observational study

Patients with left bundle branch block pattern and high cardiac risk myocardial SPECT: does the current management suffice?

Stability Analysis of Decoupled Time-stepping Schemes for the Specialized Conduction System/myocardium Coupled Problem in Cardiology

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