Prognostic Significance of Histopathology in Hodgkin's Granuloma

Lohmann, Herman J.

doi:10.1111/apm.1965.64.1.16

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Clinical Manifestations and Autopsy Findings In Patients Wit1

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1966

1981

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Cited by 5 publications

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“…None of the patient$ who had initially had lymphocytic predominance or nodular sclerosis had such types at autopsy. A shift of the material towards prognostically less favourable (HANSON 1964 andLOHMAN 1965). ) and WESTLING (1965), while VIDEBAEK (1950 indicated that the prognosis was equal for both sexes.…”

Section: Clinical Manifestations and Autopsy Findings In Patients Witmentioning

confidence: 99%

Hodgkin's Disease: Retrospective clinico-pathologic study in 149 patients

Landberg

Larsson

1969

Acta Radiologica: Therapy, Physics, Biology

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Section: Clinical Manifestations and Autopsy Findings In Patients Witmentioning

confidence: 99%

Hodgkin's Disease: Retrospective clinico-pathologic study in 149 patients

Landberg

Larsson

1969

Acta Radiologica: Therapy, Physics, Biology

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The histology of the initial relapse of Hodgkin's disease

Colby¹,

Warnke²

1980

Cancer

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The histology of relapsing Hodgkin's disease was compared with that of the original diagnostic biopsy in 56 patients. A criterion for inclusion in this study was relapse in an untreated site, thereby excluding all patients initially treated with chemotherapy. THose patients selected for study were initially treated with local radiotherapy, and relapsed outside the initial radiation fields. There was an impressive maintenance of the histologic appearance in the relapse biopsies: a change in histology was seen only in a small percentage of cases. The histologic relationship of so-called "cellular phase" of nodular sclerosing Hodgkin's disease to classical nodular sclerosing Hodgkin's disease was confirmed. Those patients with a relapse-free interval greater than one year more often had an epithelioid cell reaction (granulomatous reaction) in their biopsy material in contrast to those who relapsed in less than one year.

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Hodgkin's disease at autopsy: 1972–1977

Colby

Warnke

Hoppe

1981

Cancer

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The autopsies of 80 patients with Hodgkin's disease (HD) were reviewed. Nearly one-third of the patients died without evidence of HD at autopsy. Four patients died with clinically unsuspected HD. Infection was the most common cause of death but a significant number of patients died of complications of therapy, both benign and malignant, including five patients with hematologic or de novo lymphoid malignancies. There was wide histologic variation of HD at autopsy and many cases had a pleomorphic appearance with few of the typical features of Hodgkin's disease. Fibrous nodules interpreted as sites of eradicated HD were found in many organs, most commonly lymphoreticular. Nonfatal histopathologic effects of therapy were common and specifically assessed thyroid and gonads.

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Prognostic Significance of Histopathology in Hodgkin's Granuloma

Cited by 5 publications

References 2 publications

Hodgkin's Disease: Retrospective clinico-pathologic study in 149 patients

Hodgkin's Disease: Retrospective clinico-pathologic study in 149 patients

The histology of the initial relapse of Hodgkin's disease

Hodgkin's disease at autopsy: 1972–1977

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