Prognostic significance of EGF receptor expression in early glottic cancer

Nuclear factor‐κB expression as a novel marker of radioresistance in early‐stage laryngeal cancer

“…For example, bcl-2 has been proposed, 14,26 but also argued against, 27,28 and EGF has also been proposed 15 and shown not to be an effective prognostic marker. 28,29 Many have also argued that the status of p53 is not an appropriate marker for prognosis or clinical outcomes.…”

“…[13][14][15][16][17] Nix et al 14 reported a correlation between the bcl family and poor local control in early-stage laryngeal cancer. Demiral et al 15 reported a correlation between EGF receptor expression and poor local control in early-stage laryngeal cancer. However, because few reports exist on how those factors affect local disease controllability, 17 new biological markers are required.…”

Aggressive recurrent respiratory papillomatosis in a neonate

“…For example, the HPV early expressing protein, E5, upregulates the cell surface expression of EGFR in order to prolong the survival of virally infected cells which can facilitate viral replication and production [9]. Overexpression of the protein in human cancers has been correlated to an unfavorable prognosis and has been linked to disease progression, poor survival, and resistance to chemotherapy [10,11]. Therefore, blocking the EGFR signal transduction pathway has been evaluated as a potential target for EGFR-expressing lesions.…”

Quantification of Immune Deposits in Renal Diseases

“…First, sparing the glomerular tuft, all the surrounding areas were cleaned by manual selection at the Windows Paint Brush Program leaving only the glomerular tuft at a black background. For each captured area, the percentage of stained area with the color of selection was determined semiautomatically followed by automatic measurements by image analysis software (Mediscope, by Mustafa Sakar 5,[9][10][11][12][13] ). The software was intended for color segmentation including a determined neighborhood of colors.…”