Prognostic scoring in necrotising otitis externa

Eveleigh, Mark; Hall, Colby; Baldwin, David L.

doi:10.1017/s0022215109990491

Cited by 14 publications

(9 citation statements)

References 74 publications

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“…Local manifestations of fungal infection within the external canal are often muted, which may lead to diagnostic delays (27,30). As such, potentially severe cases of disease may be dismissed or receive lesser therapeutic interventions (5,15). The above assertions are supported by these data.…”

Section: Discussionmentioning

confidence: 60%

“…Although other MOE stratifications have been published previously, all were limited in scope and did not account for variables discussed outside of their own case series (7,8,15). Weaknesses of this study include its small sample size, retrospective nature, and the fact that the stratification was applied retroactively.…”

Section: Discussionmentioning

confidence: 99%

“…For this reason, clinical and radiographic variables predictive of these recalcitrant cases are highly sought after. Unfortunately, the literature is widely heterogeneous on this topic, with little interstudy agreement and no standardization in reporting (3,4,7,8,(10)(11)(12)(13)(14)(15)(16). To date, no attempt has been made to combine all of these described variables into a single, standardized, disease stratification protocol.…”

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confidence: 99%

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Malignant Otitis Externa

Stevens

Lambert

Baker

et al. 2015

Otology &Amp; Neurotology

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A subgroup of malignant otitis externa may exist that is not as susceptible to parenteral antibiotics and local debridement. A combination of clinical and radiographic findings may be useful for stratifying patients into severe/nonsevere categories. Patients with severe disease may be more likely to die of their disease and have worse treatment courses such that additional surgical intervention may be indicated.

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Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Malignant Otitis Externa

Stevens

Lambert

Baker

et al. 2015

Otology &Amp; Neurotology

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“…Other individual prognostic factors for estimating morbidity and mortality in necrotising otitis externa patients highlighted by previous studies, 1,4,11 such as cranial nerve involvement and radiological evidence of severe disease, defined as bony erosion or soft tissue involvement beyond the external auricular canal, were also included in our study.…”

Section: Co-morbidity and Outcome Assessmentmentioning

confidence: 99%

Necrotising otitis externa – is a poor outcome predictable? The application of a diagnosis-based scoring system in patients with skull base osteomyelitis

et al. 2021

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Background The increased incidence of necrotising otitis externa over the last decade has had a significant burden on healthcare providers. Several factors may affect outcome, and stratifying risk may allow personalised treatment. Method Retrospectively identified patients were prospectively surveyed over 12 months. The Cox proportional hazards model was used to identify predictors of poor prognosis. Results Twenty-six patients with necrotising otitis externa (average age of 80 years) were admitted from 2018 to 2019. At one year, 19 per cent mortality was observed. A high Charlson Comorbidity Index was associated with increased mortality (p = 0.03), prolonged in-patient stay (p = 0.047) and increased odds of adverse outcomes (odds ratio = 1.48, 95 per cent confidence interval = 0.26–2.67, p = 0.019). The Charlson Comorbidity Index in our prognostic model was validated using the receiver operating characteristic curve (area under the curve = 0.76). Charlson Comorbidity Index score of 5 or more independently predicted one-year morbidity and mortality (hazard ratio = 1.30, 95 per cent confidence interval = 0.94–1.79, p = 0.03). Conclusion Risk-stratifying patients may enable clinicians to holistically counsel patients and tailor their treatment to improve their prognosis and subsequently alleviate the burden of necrotising otitis externa.

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“…A differential diagnosis should consider all bacterial, fungal and viral infectious processes (Eveleigh, 2009, Paul, 2005. CONCLUSION Temporomandibular (TMJ) infection caused by Pseudomonas aeruginosa is a rare inflammatory disease with an unpleasant course.…”

Section: Case Reportmentioning

confidence: 99%

Pseudomonas Infection of the Temporomandibular Joint (TMJ) Health and Public Health Issues

Malachovsky

Janickova

Staško

et al. 2017

Acta Medica Martiniana

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A b s t r a c tThe authors describe a case of a rare infectious disease of intra-articular tissues of the temporomandibular joint caused mainly by Pseudomonas aeruginosa. In scientific literature, under the heading invasive (malignant) external otitis, we can find cases of an infectious disease of the external acoustic meatus caused by a microbial agent of Pseudomonas aeruginosa which can subsequently penetrate into structures. However, a primary affliction of the abovementioned structures has not been described. Localisation and severity of the infection requires long-term and massive treatment with antibiotics.

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Prognostic scoring in necrotising otitis externa

Abstract: A novel, systematic method of data analysis was utilised to construct a prognostic scoring model for necrotising otitis externa. This will better equip clinicians to treat this potentially fatal condition.

Cited by 14 publications

References 74 publications

Malignant Otitis Externa

Malignant Otitis Externa

Necrotising otitis externa – is a poor outcome predictable? The application of a diagnosis-based scoring system in patients with skull base osteomyelitis

Pseudomonas Infection of the Temporomandibular Joint (TMJ) Health and Public Health Issues

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