Prognostic Role of Measurement of Renal Resistive Index in Systemic Sclerosis

Sharma, Shefali; Chattopadhyay, Arghya; Sharma, Chitra Raj; Mishra, Debashish; Rathi, Manish; Prakash, Mahesh; Jain, Sanjay

doi:10.31138/mjr.32.4.345

Cited by 6 publications

(12 citation statements)

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Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

“…Systemic sclerosis is an autoimmune disease affecting internal organs and skin by inflammation, vascular dysfunction and fibrosis [129]. The vasculopathy in systemic sclerosis includes pulmonary arterial hypertension, peripheral cutaneous artery disease with Raynaud's phenomenon, ulcers or gangrene and renal arterial disease [129,130]. RRI is a noninvasive ultrasound parameter able to diagnose early renal impairment in systemic sclerosis, before irreversible structural arterial changes occur [130].…”

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

“…RRI is a noninvasive ultrasound parameter able to diagnose early renal impairment in systemic sclerosis, before irreversible structural arterial changes occur [130]. An RRI greater than 0.7 correlates with a longer duration of the disease and an increased risk for the occurrence of digital ulcers [129]. More than that, pulmonary hypertension in systemic sclerosis is associated with renal dysfunction [129,130].…”

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

“…An RRI greater than 0.7 correlates with a longer duration of the disease and an increased risk for the occurrence of digital ulcers [129]. More than that, pulmonary hypertension in systemic sclerosis is associated with renal dysfunction [129,130]. A high RRI and low GFR favor a three-fold increase risk of mortality in these patients [129].…”

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

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Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Darabont¹,

Mihalcea²,

Vinereanu³

2023

Preprint

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Initially, renal resistive index (RRI) was investigated to improve diagnosis in kidney diseases, but failed to meet this goal. Recently many papers highlighted the prognostic significance of RRI in chronic kidney disease, in the estimation of revascularization success of renal artery stenoses or the evolution of the graft and recipients in renal transplantation. Moreover, RRI gained importance in prediction of acute kidney injury in critically ill patients. Along with RRI study in renal pathology have been revealed correlations of this index with parameters of systemic circulation. The theoretical and experimental premises of this connection were reconsidered, and studies for analyzing the link between RRI and arterial stiffness, central and peripheral pressure or left ventricular flow were conducted with this purpose. A high amount of data is currently indicating that RRI is influenced more by pulse pressure and vascular compliance than by renal vascular resistance – assuming that RRI reflects the complex interplay between systemic circulation and renal microcirculation and should be considered as a marker of systemic cardiovascular risk beyond its prognostic relevance for kidney disease. In this review we will go through clinical research that revealed the implications of RRI in renal and cardiovascular disease.

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Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

Section: Rri Interaction With Other Diseasesmentioning

confidence: 99%

See 2 more Smart Citations

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Darabont¹,

Mihalcea²,

Vinereanu³

2023

Preprint

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“…42 In SSc, RRI is associated with asymptomatic renal dysfunction and may be useful in the assessment of systemic vasculopathy. 43,44 From a vasculopathy standpoint, RRI is correlated to NVC change and digital ulcer, and may have serial monitoring implications for patients with HTN. 45,46 Acute heart failure, characterized by typical symptoms and signs (i.e.…”

Section: Imaging Considerations In Htn Assessment In Ssc-sle Overlapmentioning

confidence: 99%

Evaluation of hypertension in systemic sclerosis and systemic lupus erythematosus overlap

Chew

Barnado

İkizler

et al. 2022

Journal of Scleroderma and Related Disorders

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Patients with systemic sclerosis and systemic lupus erythematosus serologies present a unique challenge to the clinician when hypertension is detected in the outpatient setting. Treatment choices for non-renal crisis hypertension are different for systemic sclerosis versus systemic lupus erythematosus. Urgent laboratory studies and, in the presence of certain symptoms, imaging assessment are indicated in systemic sclerosis and systemic lupus erythematosus overlap patients with systemic hypertension. Long-term assessment of systemic hypertension may be enhanced by advances in non-contrast imaging that serve as valuable biomarkers for progressive vasculopathy. In this review, the diagnostic approach to systemic sclerosis and systemic lupus erythematosus overlap patients presenting with hypertension is discussed.

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Analysis of risk factors for changes of renal artery resistance indexes in gout patients by ultrasound colour Doppler

Dang,

Luo,

et al. 2024

Rheumatology Advances in Practice

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Objectives Gout may disturb renal hemodynamics by promoting uric acid deposition; however, this relationship has not been elucidated with adequate clinical evidence. In this study we measured the renal artery resistance index (ARI) in patients with gout to identify the risk factors and establish predictive models for elevated renal ARI in these patients. Methods Renal artery ultrasound examination was performed in 235 primary gout patients and 50 healthy controls (HCs); subsequently, their renal interlobar ARI (RIARI), renal segmental ARI (RSARI), and overall intrarenal ARI (OIARI) were recorded. Each ARI > 0.7 was considered elevated. Results RIARI, RSARI, and OIARI were higher in patients with gout than in HCs (all p < 0.001). Nineteen (8.1%), 24 (10.2%), and 18 (7.7%) patients had elevated RIARI, RSARI, and OIARI scores, respectively. Multivariate logistic regression analyses disclosed that: age ≥ 60 years (p = 0.000), abnormal beta2 microglobulin (β2MG) (p = 0.028), and abnormal high-density lipoprotein cholesterol (HDLC) (p = 0.030) were independently associated with elevated RIARI; age ≥ 60 years (p = 0.000), and abnormal β2MG (p = 0.013) were independently related to elevated RSARI; abnormal total protein (TP) (p = 0.014) were independently linked with elevated OIARI in gout patients. Consequently, predictive models for elevated ARI were established using nomograms based on the aforementioned independent risk factors, which showed a satisfactory value for estimating elevated RIARI (area under the curve (AUC):0.929), RSARI (AUC : 0.926), and OIARI (AUC : 0.660) in patients with gout, as validated by receiver operating characteristic curves. Conclusions Renal ARI were elevated in patients with gout, whose independent risk factors included older age and abnormal β2MG, HDLC, and TP levels.

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Prognostic Role of Measurement of Renal Resistive Index in Systemic Sclerosis

Cited by 6 publications

References 0 publications

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Evaluation of hypertension in systemic sclerosis and systemic lupus erythematosus overlap

Analysis of risk factors for changes of renal artery resistance indexes in gout patients by ultrasound colour Doppler

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