Prognostic role of intestinal ultrasound in Crohn’s disease

Manzotti, Cristina; Colombo, Francesco; Zurleni, Tommaso; Maconi, Giovanni

doi:10.3748/wjg.v29.i23.3595

Cited by 2 publications

(2 citation statements)

References 67 publications

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“…Currently, the most commonly used diagnostic methods are magnetic resonance imaging (MRI) and computed tomography (CT) since they are non‐invasive and quickly evaluate active transmural inflammation and detect intestinal strictures (Table 2 ). 50 , 51 , 53 , 54 , 55 , 57 , 59 , 60 , 62 Comparing CT and MRE, a previous study suggested that the latter one is free of ionising radiation and therefore has become the most widely applied method for stricture differentiation. 66 Novel MRI techniques, such as magnetization transfer MRI (MTR) and texture analysis (TA), show promise in assessing intestinal fibrosis.…”

Section: Diagnosismentioning

confidence: 99%

“… 50 68Ga‐FAPI PET/MR enterography utilizing fibroblast activation protein (FAP) inhibition shows potential diagnostic value in detecting fibrosis. 57 Additionally, the application of AI technology has shown significant advancements in the diagnosis of intestinal fibrosis. 65 A study evaluating the efficacy of [68Ga] Ga‐FAPI‐04 PET/CT showed high sensitivity in detecting endoscopic lesions and correlated well with clinical and biomarker assessments, indicating the value of AI technology in facilitating a more comprehensive and precise evaluation of fibrosis characterization.…”

Section: Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

Intestinal strictures in Crohn's disease: An update from 2023

Liu,

Huang,

Wang

et al. 2024

UEG Journal

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Crohn's disease (CD) is a chronic inflammatory disease that leads to intestinal stricture in nearly 35% of cases within 10 years of initial diagnosis. The unknown pathogenesis, lack of universally accepted criteria, and absence of an effective management approach remain unconquered challenges in structuring CD. The pathogenesis of stricturing CD involves intricate interactions between factors such as immune cell dysbiosis, fibroblast activation, and microecology imbalance. New techniques such as single‐cell sequencing provide a fresh perspective. Non‐invasive diagnostic tools such as serum biomarkers and novel cross‐sectional imaging techniques offer a precise understanding of intestinal fibrostenosis. Here, we provide a timely and comprehensive review of the worthy advancements in intestinal strictures in 2023, aiming to dispense cutting‐edge information regarding fibrosis and to build a cornerstone for researchers and clinicians to make greater progress in the field of intestinal strictures.

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