Prognostic Performance of the CALL Score in Hospitalized Patients with COVID-19 Pneumonia

A systematic review and meta-analysis on the prevalence and impact of coronary artery disease in hospitalized COVID-19 patients

“…Numerous studies have reported that COVID-19 patients with CAD are at a higher risk of mortality [ [97] , [98] , [99] , [100] ]. A high increment in the prevalence of mortality was observed across included studies, with a prevalence rate ranging between 9% [ 33 ] and 100% [ 93 ]. A possible explanation can be drawn from the fact that the S1 sub-unit of the spike protein of severe acute respiratory syndrome (SARS-CoV-2) binds to the host cells through an angiotensin-converting enzyme (ACE2) which triggers coagulation pathways, vasoconstriction, myocarditis and fibrosis [ 101 ].…”