Prognostic Parameters in Endometrial Stromal Sarcoma: A Clinicopathologic Study in 31 Patients

Bodner‐Adler, Barbara; Obermair, Andreas; Windbichler, Gudrun; Petru, Edgar; Mayerhofer, Stephan; Czerwenka, K.; Leodolter, Sepp; Kainz, Christian; Mayerhofer, Klaus

doi:10.1006/gyno.2001.6152

Cited by 107 publications

(61 citation statements)

References 21 publications

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“…The prognosis of patients with low-grade tumors is considerably better than that of patients with other pure ovarian sarcomas. 15 This case illustrates the findings of low-grade ESS with multiple metastasis arising from an ovarian endometriotic lesion.…”

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confidence: 76%

A case of multiple metastatic low-grade endometrial stromal sarcoma arising from an ovarian endometriotic lesion

et al. 2009

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confidence: 76%

A case of multiple metastatic low-grade endometrial stromal sarcoma arising from an ovarian endometriotic lesion

et al. 2009

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“…Surgery has always been described as the most effective treatment for uterine sarcomas (2,15). However, the extent of surgery, especially the role of lymphadenectomy, is controversial.…”

Section: Discussionmentioning

confidence: 99%

“…The following characteristics have been shown to have prognostic significance for ESSs: tumor size, FIGO stage, grade, age, and menopausal status (2). The most reliable known prognostic factors are the grade of tumor and the extent of disease (3).…”

Section: Introductionmentioning

confidence: 99%

Endometrial Stromal Sarcomas: A Retrospective Analysis of 28 Patients, Single Center Experience for 20 Years

et al. 2008

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“…Because of concern about radiation exposure, frequent routine asymptomatic surveillance imaging is not recommended after primary treatment 10 . The relapse free survival depends on the tumor stage, myometrial invasion, adjuvant treatment, and bilateral salpingoopherectomy 11,12 .…”

Section: Resultsmentioning

confidence: 99%

Rare case of aub in a postmenopausal women endometrial stromal sarcoma: A case report

Bhandari¹,

Bhati²

2014

Int J of Biomed & Adv Res

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A postmenopausal, 70 year old woman (P3) visited our O.P.D with complaints of heavy bleeding per vaginum since three months, which was not associated with any pelvic or abdominal pain. O/E-Abdomen was soft non tender and no mass could be felt. Per vaginum examinationOS admitted one finger; a smooth large polyp like structure felt arising from lateral wall of uterus filling the endometrial cavity and uterus was regularly enlarged to 12 weeks with b/l adnexa free.Her routine investigations (Hb, total leucocyte counts, total platelet counts, coagulation profile, renal function and liver function tests) were within normal limts. Transvaginal USGFindings revealed presence of a solitary solid intrauterine mass of about 7x8 cms with cystic changes? Leiomyoma. Endometrial thickness ET was 3mm.Her endometrial biopsy report was suggestive of Endometrial Stromal Sarcoma (ESS)CT SCAN findings negated any metastasis or lymphovascular invasion and showed the presence of a solid smooth mass in endometrial cavity of about 7.4x6x4cms. Subsequently after counselling & oncosurgical consultation the patient with high risk consent underwent TAH & BSO. Uterus was uniformly enlarged to about 12 wks size, external surface was smooth with no growth visible on the external surface and b/l adenexa normal for age. Cut section of the specimen revealed a smooth solitary ovoid mass in the endometrial cavity measuring appx 7x5 cms in dimensions and was free from all sides from myometrium except on the left where it was attached through its broad base. Cut section of growth showed fatty degeneration but absence of any whorled appearance.Histopathological report showed the presence of endometrial stromal sarcoma with less than 50% invasion of myometrium FIGO Stage IB There were evidences of micro invasions in the lymphovascular channels.Patient had uneventful recovery & was discharged on D6 postoperatively with advice to remain in follow up and consult medical oncologist for further treatment. AbstractEndometrial Stromal Sarcomas (ESSs) are very rare malignant tumors that constitute approximately 10% of all uterine sarcomas but only around 0.2% of all uterine malignancies. The annual incidence of ESS is 1-2 per million women. It is also known as endometrial stromal myosis. The median age was 44.35 ± 6 years. Women with ESS are younger than women with other uterine sarcomas, with a median age between 45 and 57 years and, generally do not have the usual risk factors for endometrial cancer. Reported cases of endometrial stromal sarcoma in a postmenopausal woman are a rare entity.These tumors are said to be hormone dependent and therefore seems to be more common in reproductive and perimenopausal age group. Patients mainly presents with complaints of heavy vaginal bleeding and pain abdomen. ESS can be mistaken for leiomyoma. Clinical and radiology findings are suggestive of a leiomyoma. HPE remains the mainstay for diagnosis of such tumors .As these tumors are known for their recurrences close follow up of these patients is very important.

show abstract

Prognostic Parameters in Endometrial Stromal Sarcoma: A Clinicopathologic Study in 31 Patients

Cited by 107 publications

References 21 publications

A case of multiple metastatic low-grade endometrial stromal sarcoma arising from an ovarian endometriotic lesion

A case of multiple metastatic low-grade endometrial stromal sarcoma arising from an ovarian endometriotic lesion

Endometrial Stromal Sarcomas: A Retrospective Analysis of 28 Patients, Single Center Experience for 20 Years

Rare case of aub in a postmenopausal women endometrial stromal sarcoma: A case report

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