Prognostic Indicators of Quality of Life after Cholecystectomy for Biliary Dyskinesia

Geiger, Timothy M.; Awad, Ziad T.; Singh, Amolak; Davis, Wade; Thaler, Klaus; Miedema, Brent W.

doi:10.14309/00000434-200609001-00231

Cited by 3 publications

(12 citation statements)

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“…Comparison of HRQOL improvements between different time points indicated that the GIQLI and SF‐36 scores for LC patients were significantly improved by 6 months postsurgery. The improvement in LC patients after 6 months was also much larger than that in OC patients after 6 months, which is consistent with the literatures [11–13].…”

Section: Discussionsupporting

confidence: 92%

“…At 3 months postsurgery, the ES for all GIQLI dimensions correlated negatively with improvements in OC patients, which suggests that their health status was relatively poorer than that at baseline. Possible explanations for the relatively poorer health status of the OC patients include their relatively older average age, the larger percentage of males, the larger percentage of patients with only primary school education level, and the larger average wound size [11–13]. The older average age of the OC patients (61.47 years vs .…”

Section: Discussionmentioning

confidence: 99%

“…Risk factors that significantly correlated with outcome dimensions or variables were identified by univariate analysis. The related risk factors were then entered into the GEE model for multivariate regression analysis as described in the literatures [11–13].…”

Section: Methodsmentioning

confidence: 99%

“…These significant independent variables were further included in the longitudinal analysis. Restated, these effective predictive variables were included as covariates in the GEE approach because they were statistically significant in the multivariable models and are the conventional HRQOL predictors applied in the literature [11–13]. The GEE procedure under XTGEE in Stata, version 9.0 (StataCorp, College Station, TX, USA), was used for statistical analyses in this study.…”

Section: Methodsmentioning

confidence: 99%

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Health‐related quality of life in patients undergoing cholecystectomy

Hsueh

Shi

Wang

et al. 2011

The Kaohsiung J of Med Scie

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This large-scale prospective cohort study of a Taiwan population applied generalized estimating equations to evaluate predictors of health-related quality of life (HRQOL) after open cholecystectomy (OC) and laparoscopic cholecystectomy (LC) procedures performed between February 2007 and November 2008. The Gastrointestinal Quality of Life Index and Short Form-36 were used in a preoperative assessment and in 3(rd) month and 6(th) month postoperative assessments of 38 OC and 259 LC patients. The HRQOL of the cholecystectomy patients were significantly improved at 3 months and 6 months postsurgery (p<0.05). At 3 months postsurgery, HRQOL improvement was significantly larger in LC patients than in OC patients. Patient characteristics, clinical characteristics, and health care quality were also significantly related to HRQOL improvement (p<0.05). Additionally, after controlling for related variables, preoperative health status was significantly and positively associated with each subscale of the Gastrointestinal Quality of Life Index and Short Form-36 throughout the 6 months (p<0.05). Patients should be advised that their postoperative HRQOL may depend not only on their postoperative health care but also on their preoperative functional status.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Health‐related quality of life in patients undergoing cholecystectomy

Hsueh

Shi

Wang

et al. 2011

The Kaohsiung J of Med Scie

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“…In a large series of patients undergoing cholecystectomy for gallstones, relief of upper abdominal pain was associated with the pain features and negatively associated with concomitant GERD, IBS, and somatization (3). Preoperative nausea and vomiting, suggesting a global GI motility disorder, have a poorer response to cholecystectomy for biliary dyskinesia (32). This study points that gastroparesis may also be a cause of their symptoms, a finding also suggested by Deeb et al (5).…”

Section: Discussionmentioning

confidence: 99%

Cholecystectomy and Clinical Presentations of Gastroparesis

et al. 2013

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Background Many patients with gastroparesis have had their gallbladder removed. Aim To determine if clinical presentations of patients with gastroparesis differ in those with prior cholecystectomy compared to patients who have not had their gallbladder removed. Methods Gastroparetic patients were prospectively enrolled into the NIDDK Gastroparesis Registry. Detailed history and physical examinations were performed; patients filled out questionnaires including Patient Assessment of GI Symptoms (PAGI-SYM). Results Of 391 subjects with diabetic (DG) or idiopathic gastroparesis (IG), 142 (36%) had a prior cholecystectomy at the time of enrollment. Patients with prior cholecystectomy were more often female, older, married, and overweight or obese. Cholecystectomy had been performed in 27/59 (46%) of T2DM compared to 19/78 (24%) T1DM and 96/254 IG (38%) (P=0.03). Patients with cholecystectomy had more comorbidities, particularly chronic fatigue syndrome, fibromyalgia, depression, and anxiety. Postcholecystectomy gastroparesis patients had increased health care utilization and had a worse quality of life. Independent characteristics associated with prior cholecystectomy included insidious onset (OR=2.06; p=0.01), more comorbidities (OR=1.26; P<0.001), less severe gastric retention (OR(severe)=0.68; overall P=0.03) and more severe symptoms of retching (OR=1.19; P=0.02) and upper abdominal pain (OR=1.21; P=0.02), less severe constipation symptoms (OR=0.84; P=0.02), and not classified as having IBS (OR=0.51; P=0.02). Etiology was not independently associated with a prior cholecystectomy. Conclusions Symptom profiles in patients with and without cholecystectomy differ: postcholecystectomy gastroparesis patients had more severe upper abdominal pain and retching and less severe constipation. These data suggest that prior cholecystectomy is associated with selected manifestations of gastroparesis.

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Quality of Life after Laparoscopic Cholecystectomy for Biliary Dyskinesia in the Pediatric Population: A Pilot Study

Maxwell

Thompson

Richmond

et al. 2012

The American Surgeon

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This pilot study examined symptom relief and quality of life in pediatric patients who received laparoscopic cholecystectomy surgery at our institution for biliary dyskinesia. We used two validated questionnaires: the Child Health Questionnaire (CHQ-PF28), to assess general well-being, and the Gastrointestinal Quality of Life Index (GIQLI), to measure gastrointestinal-related health. After Institutional Review Board approval, all patients under the age of 18 years who underwent laparoscopic cholecystectomy for biliary dyskinesia between November 2006 and May 2010 received mailed questionnaires. Preoperative and postoperative data were retrospectively collected from respondents and included age, race, symptoms, gallbladder ejection fraction values, pathologic findings, and clinical course. Of 89 patients meeting inclusion criteria, 21 responded. Mean age at surgery was 13.08 years (range, 8 to 17 years). The most common preoperative symptoms consisted of nausea (100%), postprandial pain (90.5%), right upper quadrant pain (81.0%), and vomiting (66.7%). Mean long-term follow-up interval was 18.9 months (range, 7 to 40 months; SD 10.37). Patients with long-term symptom relief reported significantly higher GIQLI scores than those with enduring symptoms. Examination of the results from the CHQ-PF28 revealed significantly lower scores than a general U.S. pediatric sample in both the Physical and Psychosocial Summary Measures ( P < 0.05). Children experiencing long-term symptom cessation after laparoscopic cholecystectomy reported higher quality of life than those who had incomplete or only short-term relief. However, regardless of the degree of symptom relief, the degree of quality of life experienced by our study sample of patients with biliary dyskinesia is lower than that of a comparable U.S. pediatric sample.

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Prognostic Indicators of Quality of Life after Cholecystectomy for Biliary Dyskinesia

Cited by 3 publications

References 0 publications

Health‐related quality of life in patients undergoing cholecystectomy

Health‐related quality of life in patients undergoing cholecystectomy

Cholecystectomy and Clinical Presentations of Gastroparesis

Quality of Life after Laparoscopic Cholecystectomy for Biliary Dyskinesia in the Pediatric Population: A Pilot Study

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