Prognostic implications in patients with symptomatic aortic stenosis and preserved ejection fraction: Japanese multicenter aortic stenosis, retrospective (JUST-R) registry

Izumo, Masaki; Takeuchi, Masaaki; Seo, Yoshihiro; Yamashita, Eiji; Suzuki, Kazuhiro; Ishizu, Tomoko; Sato, Kimi; Aonuma, Kazutaka; Akashi, Yoshihiro J.

doi:10.1016/j.jjcc.2016.01.015

Cited by 10 publications

(7 citation statements)

References 27 publications

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“…However, we conducted a scenario analysis and sensitivity analysis to adjust for such differences. In a Japanese retrospective study, the mortality of inoperable patients with heart failure was as high as PARTNER cohort B [21]. A second limitation is that we made a number of assumptions in our data set, including procedural complications, follow-up costs, and QOL.…”

Section: Discussionmentioning

confidence: 99%

Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan

Kodera

Kiyosue

Ando

et al. 2018

Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan

Kodera

Kiyosue

Ando

et al. 2018

Journal of Cardiology

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“…A Japanese registry reported that untreated AS was associated with a mortality rate of 6.7% at 16 -month follow -up. 23 AS patients in the SILCARD registry probably had different clinical characteristics at baseline compared with other registries, which might have impacted their general prognosis. The registry mostly involved patients with symptomatic AS, excluding those with poor clinical symptoms but an increased risk of adverse events.…”

Section: Discussionmentioning

confidence: 99%

Trends in aortic stenosis diagnosis and treatment in the years 2006–2016 according to the SILesian CARDiovascular (SILCARD) database

Roleder¹,

Hawranek²,

Gąsior³

et al. 2018

Polish Archives of Internal Medicine

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INTRODUCTION During the last decade, aortic stenosis (AS) has emerged as one of the most significant concerns in cardiovascular diseases. OBJECTIVES We aimed to characterize AS patients on the basis of data derived from a local registry. PATIENTS AND METHODS We used data from the SILesian CARDiovascular (SILCARD) registry, which was developed under the agreement between the Silesian Centre for Heart Diseases in Zabrze and the Silesian branch of the Polish National Health Fund in Katowice to conduct a comprehensive analysis of patients with cardiovascular diseases in Silesian Voivodeship. RESULTS A total of 15 158 patients hospitalized with a diagnosis of AS between 2006 and 2016 were included (mean [SD] age, 69.87 [11.97] years; male patients, 7644 [50.43%]). Heart failure was reported in 4187 patients (27.62%), and coronary artery disease, in 6217 (41.01%). During the first hospitalization, aortic valve intervention was performed in 2137 patients (14.10%), and during a 12-month follow-up, in 3416 (25.32%). During the first hospitalization, percutaneous coronary intervention (PCI) was performed in 666 patients (4.39%), and coronary artery bypass grafting (CABG), in 1071 (6.71%). At 12-month follow-up, PCI was reported in 560 patients (4.15%), and CABG, in 560 (4.15%). Between 2006 and 2016, 30-day mortality was 4.35% (659 patients) and remained stable throughout the study (5.4% in 2005 vs 4.0% in 2016, P = 0.28). The 1-year mortality was 15.88% (2142 patients) and increased from 14.3% in 2006 to 16% in 2015 (P = 0.07). CONCLUSIONS The SILCARD registry has revealed an increase in the number of AS diagnoses. AS has become one of the most critical issues among cardiovascular diseases in Silesian Voivodeship.

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“…Eleven studies reported on V max , 8,9,17-25 six on MPG, 6,[26][27][28][29][30] seven on EOA, [31][32][33][34][35][36][37] and thirteen on multiple primary parameters. 5,7,[38][39][40][41][42][43][44][45][46][47][48] When all studies were pooled, any mention of error in measurement was made in less than half of the included studies (46%), with random measurement error (41%) more prevalent than systematic error (19%, Table 2).…”

Section: Systematic Reviewmentioning

confidence: 99%

Improving accuracy in diagnosing aortic stenosis severity: An in‐depth analysis of echocardiographic measurement error through literature review and simulation study

et al. 2023

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AimsThe present guidelines advise replacing the aortic valve for individuals with severe aortic stenosis (AS) based on various echocardiographic parameters. Accurate measurements are essential to avoid misclassification and unnecessary interventions. The objective of this study was to evaluate the influence of measurement error on the echocardiographic evaluation of the severity of AS.Methods and resultsA systematic review was performed to examine whether measurement errors are reported in studies focusing on the prognostic value of peak aortic jet velocity (Vmax), mean pressure gradient (MPG), and effective orifice area (EOA) in asymptomatic patients with AS. Out of the 37 studies reviewed, 17 (46%) acknowledged the existence of measurement errors, but none of them utilized methods to address them. Secondly, the magnitude of potential errors was collected from available literature for use in clinical simulations. Interobserver variability ranged between 0.9% and 8.3% for Vmax and MPG but was higher for EOA (range 7.7%‐12.7%), indicating lower reliability. Assuming a circular left ventricular outflow tract area led to a median underestimation of EOA by 23% compared to planimetry by other modalities. A clinical simulation resulted in the reclassification of 42% of patients, shifting them from a diagnosis of severe AS to moderate AS.ConclusionsMeasurement errors are underreported in studies on echocardiographic assessment of AS severity. These errors can lead to misclassification and misdiagnosis. Clinicians and scientists should be aware of the implications for accurate clinical decision‐making and assuring research validity.

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Prognostic implications in patients with symptomatic aortic stenosis and preserved ejection fraction: Japanese multicenter aortic stenosis, retrospective (JUST-R) registry

Abstract: This retrospective study demonstrated the current associations between the types of AS symptoms and prognosis in Japanese patients with severe AS.

Cited by 10 publications

References 27 publications

Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan

Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan

Trends in aortic stenosis diagnosis and treatment in the years 2006–2016 according to the SILesian CARDiovascular (SILCARD) database

Improving accuracy in diagnosing aortic stenosis severity: An in‐depth analysis of echocardiographic measurement error through literature review and simulation study

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