2015
DOI: 10.1253/circj.cj-14-0865
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Prognostic Impact of Statin Use in Patients With Heart Failure and Preserved Ejection Fraction

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Cited by 60 publications
(45 citation statements)
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References 40 publications
(37 reference statements)
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“…In a clinical study, Nochioka et al showed that statin is effective for patients with heart failure and preserved ejection fraction to reduce infection deaths. 21 Another study has shown that early statin treatment in patients with ACS improves biomarkers of inflammation. 22 It is not known, however, as to what extent these activities contribute to the reduction of inhospital mortality in AMI patients.…”
Section: 469mentioning
confidence: 99%
“…In a clinical study, Nochioka et al showed that statin is effective for patients with heart failure and preserved ejection fraction to reduce infection deaths. 21 Another study has shown that early statin treatment in patients with ACS improves biomarkers of inflammation. 22 It is not known, however, as to what extent these activities contribute to the reduction of inhospital mortality in AMI patients.…”
Section: 469mentioning
confidence: 99%
“…Связь между исходным индексом миокарда левого желудочка и степенью его изменения за время исследования ОРИГИНАЛЬНЫЕ СТАТЬИ § статинов отмечались уменьшение содержания в миокар-де нитротирозина (маркера активности окислительных процессов) и повышение активности протеинкиназы G, а также уменьшение размера кардиомиоцитов и их оста-точного напряжения [8]. В ряде небольших исследований, а также в одном регистре использование статинов улуч-шало прогноз больных с СНСФВ [13][14][15]. Наличие системного воспаления, как «пускового» механизма развития СНСФВ, оправдывает использо-вание статинов не только у больных с уже имеющейся СНСФВ, но и у бессимптомных больных с высоким риском развития СНСФВ, каковыми собственно и явля-ются больные с компенсированным гипертоническим сердцем.…”
Section: у больных с гипертоническим сердцем статины препятствуют разunclassified
“…Moreover, statins prescribed at earlier stages of CHF might better improve clinical prognosis than in later stages [31] . Recently, Nochioka et al [32] studied the effect of statin treatment on mortality in a large-scale cohort of patients with HF with preserved ejection fraction (HFpEF). The results of that study indicated that statin treatment improved mortality rates in HFpEF patients, which was mainly attributable to reductions in SCD and non-CV death.…”
Section: Statin Therapy and Scdmentioning
confidence: 99%