Prognostic Impact of Pulmonary Artery Pulsatility Index (PAPi) in Patients With Advanced Heart Failure: Insights From the ESCAPE Trial

Pulmonary artery pulsatility index: physiological basis and clinical application

“…examined the prognostic value of PAPi in cardiogenic shock using the dataset from the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) trial and registry. However, pulmonary artery catheterization was performed only in a subset of patients in the trial and the registry, and less than half the patients from the trial and about a third from the registry had the complete set of data for this analysis – a major limitation similar to the study by Kochav et al . This study by Lala et al .…”

“…Kochav et al . studied the prognostic value of PAPi in patients with advanced heart failure, using a cohort from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial.…”

“…Kochav et al 26 studied the prognostic value of PAPi in patients with advanced heart failure, using a cohort from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial. Of the 433 patients enrolled, 202 patients had right heart catheterization data available at the baseline time point, from which 190 patients were included.…”

Right Ventricular Failure

“…Magnetic resonance imaging provides specific information about RV volume but is limited in patients with implantable pacemakers and defibrillators. 2,10…”

“…1 Right ventricular dysfunction, defined as evidence of abnormal RV structure or function, 1 is a powerful and independent predictor of mortality in patients with chronic heart failure. 2 This article describes the normal structure and function of the RV, causes of RV dysfunction leading to RV failure, diagnostic and emerging hemodynamic assessments, and management of RV failure in the critical care unit.…”