Prognostic Impact of Computed Tomography-Derived Abdominal Fat Area on Transcatheter Aortic Valve Implantation

Abstract

there have been no reports on the individual prognostic value of body fat. The aim of the present study was therefore to evaluate the effect of abdominal fat on long-term clinical outcomes in patients undergoing TAVI. To clarify this, we focused on abdominal fat area, including the visceral fat area (VFA) and subcutaneous fat area (SFA) evaluated on computed tomography (CT), and evaluated their individual effects on long-term clinical outcomes such as all-cause mortality and re-hospitalization due to worsening heart failure in patients undergoing TAVI. Methods Subjects This was a retrospective study of 100 consecutive patients with severe AS undergoing TAVI between

Evaluation of objective nutritional indexes as predictors of one-year outcomes after transcatheter aortic valve implantation

“…This is considered to be due to a patient's diminished physiological reserve, which is expressed as frailty. Previously, many frailty factors such as body mass index, subcutaneous fat area, gait speed, and multidimensional geriatric assessments have been reported to be useful for risk stratification of these high-risk patients [4][5][6][7][8][9]. Our results showed that objective nutritional indexes such as the CONUT score and PNI might also be useful to assess a patient's frailty and for risk stratification.…”

“…Moreover, the CONUT score and PNI had better predictive values than GNRI. Malnutrition, which was evaluated by the CONUT score, PNI, or GNRI, is known to be well associated with frailty, and its correlation with prognosis in various diseases has been shown in previous reports [2][3][4][5][6][7][8][9][10][11]. Shibata et al have reported that GNRI is an important surrogate marker for predicting worse clinical outcomes even in patients undergoing TAVI [23].…”

“…Therefore, preoperative recognition of patients at risk of early mortality or re-hospitalization is critical for risk stratification and appropriate therapeutic intervention in patients who are candidates for TAVI. For this reason, many prognostic factors have been identified in this population previously [2][3][4][5][6][7][8][9].…”

3D-segmentation and characterization of visceral and abdominal subcutaneous adipose tissue on CT: influence of contrast medium and contrast phase

“…However, the utility of contrast enhanced scans (CES) for body composition analysis with the possibility of comparing the obtained values to other studies would be most convenient as many patients require a CES for other aspects of clinical decision making. Some studies already utilize fat segmented from CES for risk assessment, but comparing these results to those of previous works would only be possible with severe limitations (17,18).…”

Association Between Major Adverse Cardiovascular Events and the Ratio of Subcutaneous Fat Area to Visceral Fat Area in Patients Who Have Undergone Multidetector Row Computed Tomography

“…33 Because SFA and VFA, which contribute to AC, are considered to be important indicators, SFA and/or VFA may be more important markers than AC. 34,35 The volume of SF that can accumulate is predetermined and varies according to the individual. When this limit is exceeded, adipocytes will accumulate as VF.…”