Prognostic factors of pediatric glaucoma: a retrospective study

Moschos, Marilita M.; Nitoda, Eirini; Fenzel, Isabelle; Song, Xuefei; Langenbucher, Achim; Kaesmann, Barbara; Seitz, Berthold; Gatzioufas, Zisis

doi:10.1007/s10792-018-0819-0

Cited by 14 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Significantly higher preoperative IOP (mean 39.47 ± 2.18 mmHg, p = .000016) in infants from group I confirms the critical role of this factor in corneal damage and development of Haab's striae. Early trabeculectomy successfully lowered IOP in both our groups, which is in keeping with the findings of other studies (3,5,12). The mean postoperative IOP below 18 mmHg achieved in group I is also comparable to the results of other studies (13).…”

Section: Discussionsupporting

confidence: 92%

“…Primary trabeculectomy was performed between the age of 7 days and 12 months in all eyes from both groups. Our results do not confirm poor prognosis associated with younger age at diagnosis or surgery in PCG patient and the outcomes are similar to results of other surgeons (2,3,5,8).…”

Section: Discussioncontrasting

confidence: 51%

“…Various authors consider axial length and corneal diameter to be important factors in diagnosis and monitoring of patients with PCG (5,8). In our study, there was no difference in baseline axial length and corneal diameter between the groups.…”

Section: Discussionmentioning

confidence: 42%

“…The age has been shown as an important prognostic factor in PCG (5,6). Diagnosis before 2 month or after 2 years of age is associated with worse prognosis (6).…”

Section: Discussionmentioning

confidence: 99%

“…PCG has the best prognosis of all types of paediatric glaucoma (1,5), with 52% to 79% of patients achieving visual acuity of 20/50 (0.4) or better (1), and such postoperative visual acuity is estimated to be a good functional result in buphthalmic eyes (9,10). We achieved comparable mean BCVA in patients with and without Haab's striae, which contrasts with the results of other authors who obtained worse visual outcomes in children with Haab's striae (11).…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Evaluation of functional and morphological parameters in eyes with primary congenital glaucoma after trabeculectomy in the long-term follow-up

Koraszewská-Matuszewska¹,

Nita²,

Grzybowski³

2018

View full text Add to dashboard Cite

Aim: Primary congenital glaucoma is the most prevalent type of primary paediatric glaucoma. The aim of the study was to estimate functional and morphological parameters in eyes with primary congenital glaucoma, with and without Haab's striae, after classic trabeculectomy in the long-term follow-up. Material and methods: 41 eyes of 27 children aged 7 days to 12 months at primary trabeculectomy with (group I) and without Haab's striae (group II) were reviewed. The best corrected visual acuity, intraocular pressure, central corneal thickness, axial biometry, corneal horizontal diameter, refraction, central endothelial cell density, cup-to-disc ratio, and perimetric mean deviation were analysed. Results: The mean follow-up was 11.4 years. The mean age of operated infants was 5.65 months (group I) and 4.41 months (group II). The mean intraocular pressure before trabeculectomy was significantly higher and endothelial cell density was significantly lower in group I than in group II. The mean myopic refractive error was significantly higher in group I than in group II. There was no difference in best corrected visual acuity, central corneal thickness, axial biometry, corneal horizontal diameter, and perimetric mean deviation between the two groups. Conclusions: The visual function in patients with primary congenital glaucoma after successful trabeculectomy performed in infancy is satisfactory, despite the presence of Haab's striae, impaired corneal structure and decreased endothelial cell density. High intraocular pressure before treatment is an important risk factor for the development of Haab's striae. Classic trabeculectomy is a good first-line surgical procedure in the treatment of primary congenital glaucoma with and without Haab's striae.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussioncontrasting

confidence: 51%

Section: Discussionmentioning

confidence: 42%

“…The age has been shown as an important prognostic factor in PCG (5,6). Diagnosis before 2 month or after 2 years of age is associated with worse prognosis (6).…”

Section: Discussionmentioning

confidence: 99%